Johns Hopkins Bayview is a vibrant academic medical center, offering services that range from primary care and emergency medicine, to specialized centers.

Our expert clinicians at The Johns Hopkins Division of Gastroenterology and Hepatology at Bayview Medical Center offer a full range of gastroenterology and hepatology services including endoscopy and motility studies.

Oct 4, 2024 · Hepatitis B is a serious liver infection caused by the hepatitis B virus (HBV). For most people, hepatitis B is short term, also called acute. Acute hepatitis B lasts less than six months. But for others, the infection lasts more than six months and is called chronic.

HBV cccDNA 以微小染色体的形式稳定地存在于感染肝细胞核内，是HBV感染慢性化和难以治愈的关键。 cccDNA的来源包括初始感染和胞内复制回补2种途径。 由其转录的pgRNA既是核心抗原和 P蛋白 的mRNA，又可作为逆转录模板形成新的rcDNA。 新合成的rcDNA一方面可成为有感染性的完整病毒颗粒，再感染新的正常肝细胞；另一方面，新合成的rcDNA也可进入细胞核，经过修复后回补核内cccDNA，以维持肝细胞核内cccDNA池的稳定性。 NAs药物的作用机制正是通过与 …

Hepatitis B virus (HBV) infection remains a global public health problem with changing epidemiology due to several factors including vaccination policies and migration. This Clinical Practice Guideline presents updated recommendations for the …

Mar 25, 2023 · Hepatitis B virus (HBV) infection is a major public health problem, with an estimated 296 million people chronically infected and 820 000 deaths worldwide in 2019.

Hepatitis B (HBV) infection is a major public health problem and cause of chronic liver disease. The 2024 HBV guidelines provide updated evidence-informed recommendations on key priority topics.

Johns Hopkins Bayview Medical Center is recognized for excellence in many medical specialties, including bariatric surgery, hip and knee replacement, spine surgery, stroke care and behavioral health. For more information about referrals or appointment …

Nov 24, 2018 · Chronic hepatitis B virus infection is a global public health threat that causes considerable liver-related morbidity and mortality. It is acquired at birth or later via person-to-person transmission. Vaccination effectively prevents infection and chronic hepatitis B …

Chronic hepatitis B (CHB) remains a major global health problem affecting more than 240 million people with high liver-related morbidity and mortality worldwide.