
JAK2 Mutation – Effects and Questions | Mayo Clinic Connect
There was an article I saw from the National Institute of Health (NIH) that tested well over 10,000 people and tracked them for many years. From those 10,000+ people, they found only 15 that had the JAK2 mutation and determined that only 3 of the 15 died as a direct result of their disease well into their 70's or 80's.
Jak2 positive, biopsy next: Does it mean I have blood cancer?
2022年6月21日 · I was diagnosed with MGUS, a plasma cell neoplasm, in 2017. Earlier this year, my blood and platelet counts became extremely elevated. A blood test done for JAK2 came back positive. A bone marrow biopsy was then done to check my MGUS. It confirmed the JAK2 diagnosis along with additional findings on my PCN.
Need help newly diagnosed with a high platelet count and the …
2024年9月23日 · I am 80 and have been dealing with ET JAK2 for over two years. The standard dose of HU (Hydroxyurea) is 500 mg capsules. I have taken one at different timeframes. I started one daily…had a little lightheadness, slight headache, but generally okay. Eventually I dropped to one every other day. Now taking one four days a week.
JAK2 Mutation and enlarged spleen: What might it mean?
2024年10月25日 · We all have a JAK2 gene, but sometimes it turns itself “on”into something like a mutation. In my case, I have ET w/JAK2. That’s essential thrombocythemia (high platelets). For almost 2 years, I’ve been on one baby aspirin every morning (and a second when I fly long distance). Aspirin doesn’t reduce platelets, but it makes them less ...
Blood Cancer – JAK2 – Autoimmune- Confusion - Mayo Clinic …
2023年4月1日 · JAK2 mutations can cause various bone marrow disorders. These are known as myeloproliferative neoplasms (MPNs), where the bone marrow produces too many blood cells. Some of the symptoms you have such as the enlarged spleen, itching, high …
JAK2 Mutation, Low Iron and High Platelet count
2020年11月25日 · I also have the JAK2 mutation and a high platelet count. So I’m on Hydroxyurea to reduce the platelet count. I also have several other gene mutations including the splicing genes SRSF2 and SBF31 which is on the MDS side. Not sure how your Hematologist can say you were born with the JAK2 mutation because exposure to toxins can cause gene ...
Jak2 Detected, Healthy otherwise, What's next? - Mayo Clinic …
2023年9月25日 · Expectedly so, based on Jak2 detection and blood counts level, doctor has officially stamped diagnosis for PV. Further blood tests, spleen ultrasound and bone marrow biopsy are ordered and will be scheduled over next couple of weeks.
Jak2 positive, biopsy next: Does it mean I have blood cancer?
2024年9月16日 · I was checked for JAK2 by a rheumatologist looking to see if I had rheumatoid arthritis. I have no JAK2 mutation and do not have rheumatoid arthritis but do have one enlarged right finger proximal interphanageal joint huge enlargement with no pain and an enlarged right sternoclavicular joint also with no pain.
JAK2 V617F positive, now what? | Mayo Clinic Connect
2023年10月31日 · There are a number bone marrow disorders related to the JAK2 gene mutation called Myeloproliferative neoplasms. These are a type of blood cancer that occur when blood stem cells produce too many of one or more types of blood cells, including red or white blood cells, and platelets
Medication for JAK2 - Mayo Clinic Connect
2019年3月28日 · For me, the JAK2 mutation causes a high platelet count. I was put on Hydroxyurea and my platelet count dropped from 847,000 to 224,000 within 4 months. The doctors at Sloan have not started any treating for the MDS issue as they were concerned about the high platelet count which was my worst symptom.