In biology and other experimental sciences, an in silico experiment is one performed on a computer or via computer simulation software. The phrase is pseudo-Latin for 'in silicon' (correct Latin: in silicio), referring to silicon in computer chips.

In silico studies In silico is an expression used to mean “performed on computer or via computer simulation.” The expression in silico was first used in public in 1989 in the workshop “Cellular Automata: Theory and Applications” in Los Alamos, New Mexico.

2021年10月27日 · The term ‘in silico’ refers to computational models that investigate pharmacological hypotheses using methods such as databases, data analysis tools, data mining, homology models, machine ...

2020年4月25日 · In vivo，意思是在活体中的，实验在完整的活得生物体中进行。 In vitro，意思是在玻璃中的，实验在生物体外，通常是实验玻璃器皿中进行。 这种实验的优点是可以被精确的控制，缺点是实验状态不能很好的反映真实的生物体状态。 Ex vivo，意思是活体外的，其定义是“它是指在生物体以外的人工环境中，以最小自然条件的变化在活组织内或活组织上进行的实验或测 …

An in silico clinical trial, also known as a virtual clinical trial, is an individualized computer simulation used in the development or regulatory evaluation of a medicinal product, device, or intervention.

In a nutshell, in silico means “using computer simulations and models to research complicated biological, chemical, and physical systems.” In silico methods are employed in a variety of fields, such as drug design, environmental research, and chemical processes.

2023年8月3日 · In silico drug design, also commonly known as computer-aided drug design (CADD), involves using computational techniques and models to identify drug-like molecules using bioinformatics tools. In silico methods analyze and predict the biological activity of potential drug candidates, and also predict their physicochemical properties.

In Silico Pharmacology is an interdisciplinary journal focusing on computational approaches in drug design and multiscale analysis of bioactive substances. Bridges the gap between theory and experimental studies in ligand-target interactions and associated drug …

2022年3月16日 · In silico studies are biological experiments carried out entirely on a computer, or via a computer simulation. As such, they are by far the newest of the three research methods (the first took place in 1989).

2025年3月8日 · In silico docking studies play a pivotal role in modern drug discovery. They provide a cost-effective and time-efficient method to screen large libraries of compounds, predict how they interact with targets, and identify promising leads for further development.