Insulin-like growth factor 1 receptor - Wikipedia
It is a transmembrane receptor that is activated by a hormone called insulin-like growth factor 1 (IGF-1) and by a related hormone called IGF-2. It belongs to the large class of tyrosine kinase …
胰岛素(Insulin)及其受体家族 - 知乎 - 知乎专栏
胰岛素受体家族成员在与各自的配体（如胰岛素 (insulin)、胰岛素样生长因子 ( IGF-1或IGF-2)）结合后，通过一系列的结构构象变化，激活胞内酪氨酸激酶，起始胞内信号传导，在生物体内发 …
胰岛素样生长因子 - 百度百科
胰岛素样生长因子（insulin like growth factor，IGF）是一组具有促生长作用的多肽类物质，其分泌细胞广泛分布在人体肝、肾、肺、心、脑和肠等组织中。 IGF族有IGF-Ⅰ和IGF-Ⅱ两种。 IGF …
胰岛素样生长因子1受体 - 维基百科，自由的百科全书
胰岛素样生长因子1受体 （英語： insulin-like growth factor 1 receptor，IGF-1R）是人类 细胞 表面发现的 蛋白质，是激素 胰岛素样生长因子1 （IGF-1）的 细胞表面受体，属于 酪氨酸激酶 受 …
IGF1R Gene - GeneCards | IGF1R Protein | IGF1R Antibody
Dec 25, 2024 · IGF1R (Insulin Like Growth Factor 1 Receptor) is a Protein Coding gene. Diseases associated with IGF1R include Insulin-Like Growth Factor I and Growth Delay Due …
IGF-1(胰岛素样生长因子) - 知乎 - 知乎专栏
IGF-1 (胰岛素样生长因子)是与胰岛 素密切相关的生长因子。 它携带与胰岛素相同量的氨基酸，并 负责对 GH 的合成代谢反应。 IGF-1 是儿童生长中的重要因子， 并且在成人中是高度合成代 …
Structural basis of the activation of type 1 insulin-like ... - Nature
Oct 8, 2019 · Type 1 insulin-like growth factor receptor (IGF1R) is a receptor tyrosine kinase that regulates cell growth and proliferation, and can be activated...
胰岛素受体亚型和胰岛素生长因子样受体：对细胞信号传导、癌发 …
该综述强调了 IR 和 IGFR 之间复杂的相互作用，导致抗 IGFR 药物产生耐药性。 因此，两种受体的双重靶向可能为克服化疗耐药性提供更有效的策略。 总之，这篇综述揭示了 IR 和 IGFR 在 …
Definition of IGFR - NCI Dictionary of Cancer Terms
A protein found on the surface of some types of cells that binds to insulin-like growth factor (IGF). This causes the cells to grow and divide. IGFR is found at high levels on the surface of several …
Insulin receptor (IR) and insulin-like growth factor receptor 1 (IGF …
Insulin and insulin-like growth factor (IGF) signaling system, commonly known for fine-tuning numerous biological processes, has lately made its mark as a much sought-after therapeutic …