Interleukin 33 (IL-33) is a protein that in humans is encoded by the IL33 gene. [5] Interleukin 33 is a member of the IL-1 family that potently drives production of T helper-2 (Th2)-associated cytokines (e.g., IL-4).

2016年9月19日 · Interleukin-33 (IL-33), which was identified as a member of the IL-1 family approximately 10 years ago 1, is now recognized to have a key role in innate and adaptive immunity, contributing to...

Interleukin (IL)-33 is a key cytokine involved in type 2 immunity and allergic airway diseases. Abundantly expressed in lung epithelial cells, IL-33 plays critical roles in both innate and adaptive immune responses in mucosal organs.

2022年8月1日 · Interleukin-33 (IL-33), a member of the IL-1 family, is an alarmin cytokine with crucial roles in tissue homeostasis and repair, type 2 immunity, allergic and non-allergic inflammation, viral infection, and cancer.

IL-33 is a newly characterized cytokine that amplifies both innate and adaptive immune responses. In this review, we discuss the role of IL-33 and its receptor ST2 in the pathogenesis of pulmonary inflammatory diseases. The IL-33/ST2 pathway is a potential therapeutic target in the treatment of lung diseases. II.IL-33

Interleukin-33 (IL-33), a member of the IL-1 family, is an alarmin cytokine with crucial roles in tissue homeostasis and repair, type 2 immunity, allergic and non-allergic inflammation, viral infection, and cancer.

IL-33 plays important roles in type-2 innate immunity via activation of allergic inflammation-related eosinophils, basophils, mast cells, macrophages, and group 2 innate lymphoid cells (ILC2s) through its receptor ST2.

Interleukin-33 (IL-33) - a member of the IL-1 family - was originally described as an inducer of type 2 immune responses, activating T helper 2 (T H 2) cells and mast cells. Now, evidence is accumulating that IL-33 also potently stimulates group 2 …

This study documents the intranuclear properties of IL-33. IL-33 was found to be heterochromatin-associated in human endothelial cells, exerting a repressive effect on DNA transcription.

2016年1月19日 · Interleukin 33 (IL-33) is a member of the IL-1 family of cytokines with a growing number of target cells and a plethora of biological functions. Although it has commonalities with other IL-1...