Hypocomplementemic urticarial vasculitis (HUV) is a rare form of vasculitis characterized by inflammation of the small blood vessels and low levels of complement proteins in the blood. HUV causes recurrent episodes of hives (urticaria) and painful skin lesions that itch or burn.

HUV Syndrome (HUVS). HUVS is a rare, distinct, and potentially severe form of UV with multiorgan involvement.

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Unfortunately, there are no known specific therapies for HUV. Treatments include systemic corticosteroids, dapsone, colchicine, hydroxychloroquine, and various immunosuppressant medications, such as methotrexate, mycophenolate, and azathioprine. Newer targeted medications, including omalizumab and belimumab, have also been used. [6]

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Hypocomplementemic urticarial vasculitis syndrome (HUVS) is a rare leukocytoclastic vasculitis characterized by recurrent urticarial lesions and hypocomplementemia, often associated with other systemic symptoms such as fever, arthralgias, arthritis, abdominal pain as well as ocular, renal, pulmonary and gastrointestinal involvement.

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2019年3月13日 · Hypocomplementemic urticarial vasculitis (HUV) is more common in women but can be seen in both genders and represents about 15% of patients with urticarial vasculities (UV). Characteristic findings on physical examination