Dec 25, 2024 · HSPA1B (Heat Shock Protein Family A (Hsp70) Member 1B) is a Protein Coding gene. Diseases associated with HSPA1B include Pulmonary Edema and Acute Pancreatitis. Among its related pathways are Autodegradation of the E3 …

Data show that HSPA1B exerts a positive effect on hepatocellular carcinoma (HCC) cell growth and may be involved in the HBV-miR- 340- 5p- ATF7 axis. Downregulation of HSPA1b impaired mesenchymal stem cell osteogenic and chondrogenic differentiation.

Jan 5, 2025 · Clinical resource with information about HSPA1B, and available tests. There are links to practice guidelines and authoritative resources like GeneReviews, PubMed, MedlinePlus, PharmGKB and clinicaltrials.gov.

In our study, we found that the expressions of HSPA1B, HSPA4, HSPA5, HSPA6, HSPA8, HSPA9, HSPA13, and HSPA14 were significantly increased, while those of HSPA1A, HSPA2, HSPA7, and HSPA12B were significantly decreased in colon cancer tissues.

HSPA1B is a prognostic marker in Kidney renal clear cell carcinoma, Pancreatic adenocarcinoma

Oct 26, 2021 · In our study, we found that the expressions of HSPA1B, HSPA4, HSPA5, HSPA6, HSPA8, HSPA9, HSPA13, and HSPA14 were significantly increased, while those of HSPA1A, HSPA2, HSPA7, and HSPA12B were significantly decreased in colon cancer tissues.

Dec 16, 2022 · Given the significant role the heat shock protein Hsp70 plays in modulating cellular homeostasis in several chronic inflammatory disorders, the genetic variation of the inducible HSP70 (HSPA1B) gene may impact protein expression and disease phenotype.

Oct 7, 2019 · HSPA1 is among the best characterized cancer-related chaperones, while the significance of HSPA2 for cancer remains poorly understood. Previously we found that in primary NSCLC, HSPA1 was...

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Two copies of the Hsp70 gene, HSPA1A and HSPA1B, are located on chromosome 6p21. The coding regions of HSPA1A and HSPAIB are intronless and nearly identical, however, promoter and 3' UTR sequences are different.