Hep 3B2.1-7 [Hep 3B, Hep-3B, Hep3B] is a cell line exhibiting epithelial morphology that was isolated from liver tissue derived from an 8-year-old, Black youth with liver cancer. This cell line contains an integrated hepatitis B virus genome.

Hep3B分离自8岁美国黑人男童的肝癌组织. 细胞形态跟HepG2类似, 呈上皮细胞, 电镜下观察胞浆里面很多粗大的黑颗粒, 同样喜抱团贴壁生长; 其在裸鼠中能致瘤, 但基本不转移. HBV阳性, 这与HepG2不同, 这株细胞整合了完整的HBV基因组，可用于HBV感染后发展致癌相关研究。 该细胞系于1982年从一名患有肝癌的57岁日本男性肝癌组织标本上培养而得。该细胞AFP阳性，高度 …

HEP3B is a tumorigenic hepatocellular carcinoma cell line capable of forming tumours when injected into an immunocompromised mouse. This aids in studying cancer progression and development using HEP3B xenograft models. HEP3B P53 status

Human hepatocellular carcinoma cell lines secrete the major plasma proteins and hepatitis B surface antigen. Detection of hepatitis B virus-specific DNA in the genomes of human hepatocellular carcinoma and liver cirrhosis tissues. Chromosomes of human hepatoma cell lines.

As cellular models for in vitro liver cancer and toxicity studies, HepG2 and Hep3B are the two most frequently used liver cancer cell lines. Because of their similarities they are often treated as the same in experimental studies.

the cell line contains parts of the hepatitis B virus (HBV) genome integrated into the eukaryotic genome. The HBV surface antigen (HBsAg) is expressed, but no active viruses are produced by the cells. The cells can thus be handled under biosafety level 1.

Analysis of Liver Cancer Cell Lines Identifies Agents With Likely Efficacy Against Hepatocellular Carcinoma and Markers of Response.

Maintaining healthy cells is the key to experimental success and reproducible research results. To give you confidence in the health of your cells every step of the way, we’ve highlighted the technologies and products within cell biology that are critical to maintaining optimal cell health.

Materials and methods: Using 3- (4,5-dimethylthiazol-2-yl)-5- (3-carboxymethoxyphenyl)-2- (4-sulfophenyl)-2H-tetrazolium (MTS) assay, we investigated various and opposing effects in hepatocellular carcinoma cells, Hep-G2 and Hep-3B with different p53-status.

To identify the action mechanism of coptisine-induced apoptosis in Hep3B cells, we investigated the phosphorylation status of the mitogen-activated protein kinases (MAPKs) signaling pathway including the extracellular signal-regulated kinase (ERK), c …