293 [HEK-293] is a cell line exhibiting epithelial morphology that was isolated from the kidney of a human embryo. This cell line can be used in industrial biotechnology and toxicology research. It has applications in efficacy testing and viruscide testing.

The human cell line, HEK293, have emerged to be the main production platform for therapeutic viral vectors. Advancements in cell line developments would see more HEK293 clones or derivatives developed for growth in a serum-free suspension …

HEK293 is a cell line derived from human embryonic kidney cells grown in tissue culture. They are also known, more informally, as HEK cells. This particular line was initiated by the transformation and culturing of normal HEK cells with sheared adenovirus 5 DNA.

Nov 12, 2024 · There are several derived sublines of hek293 cells, each with distinct characteristics and applications. Pricella introduces the key features and uses of four major hek293 subtypes: 293T, 293F, 293H, and 293S.

Feb 6, 2023 · HEK293 cells are Human Embryonic Kidney cells, originally isolated and grown by Dutch biologist Alex Van der Eb in the early 1970s. They were transfected with sheared adenovirus 5 (Ad5) DNA by Frank Graham, a postdoc in Van der Eb’s lab.

The HEK293 cell line is a permanent line established from primary embryonic human kidney, which was transformed with sheared human adenovirus type 5 DNA. The adenoviral genes expressed in this cell line allow the cells to produce very high levels of recombinant proteins.

Sep 3, 2014 · Nature Communications - The human embryonic kidney 293 (HEK293) cell lineage is widely used in cell biology and biotechnology. Here, the authors apply whole genome resequencing methods to...

Jun 18, 2021 · Human Embryonic Kidney 293 (HEK 293) cells are one of the most frequently used cell lines for biotechnology and research studies. These cells are quite popular because of their distinct properties like fast-growing, robustness, and ease of maintenance and transfection.

The HEK293 cell line has earned its place as a producer of biotherapeutics. In addition to its ease of growth in serum-free suspension culture and its amenability to transfection, this cell line’s most important attribute is its human origin, which ...

Aug 26, 2023 · HEK 293 has a modal chromosome number of 64 and is described as hypotriploid, meaning it has less than three times the chromosome number of a haploid human gamete. They also have chromosomal abnormalities, such as three copies of X chromosomes and four copies of chromosomes 17 and 22.