Histone deacetylase 7 is an enzyme that in humans is encoded by the HDAC7 gene. [5][6][7] Histones play a critical role in transcriptional regulation, cell cycle progression, and …

2024年12月25日 · HDAC7 (Histone Deacetylase 7) is a Protein Coding gene. Diseases associated with HDAC7 include Hematologic Cancer and Epilepsy. Among its related …

2024年2月27日 · HDAC7 facilitates β-catenin redistribution to the nucleus by deacetylating β-catenin and inhibiting its phosphorylation, which results in that the nuclear accumulation of β …

HDAC7 promotes the growth of human and mouse AEL cells both in vitro and in vivo through its non- enzymatic functions. Our study provides experimental evidence that TP53 deficiency …

2022年3月11日 · HDAC7 overexpression remarkably enhanced cell migration verified by scratch wound assay and transwell assay (Fig. 2a and b) and suggested that HDAC7 overexpression …

2010年12月1日 · In this study, we performed RNA interference targeting HDAC7 in human tumor cell lines and demonstrated that HDAC7 silencing was effective in inhibiting cancer cell …

HDAC7 is involved in regulation of myocyte migration and differentiation. Known interaction partners of class IIa HDAC7 are myocyte enhancer factors - MEF2A, -2C, and -2D, 14-3-3 …

2020年5月4日 · We found that SIK1 phosphorylated and stabilized histone deacetylase 7 (HDAC7) protein during cardiac stress, an event that is required for pathologic cardiomyocyte …

We found that HDAC1 and HDAC3 inhibition or knockdown results in HDAC7 downregulation, which is associated with a decrease in histone 3 lysine 27 acetylation (H3K27ac) at …

2011年4月15日 · We report that HDAC7 is exported from the cell nucleus during positive selection in mouse thymocytes and that it regulates genes mediating the coupling between TCR …