H3S10P is an epigenetic modification to the DNA packaging protein histone H3. It is a mark that indicates the phosphorylation the 10th serine residue of the histone H3 protein. Depending on …

2020年10月14日 · Phosphorylation of serine 10 on histone H3 (H3S10ph) is an unique histone modification as it is involved in two structurally opposed processes: transcriptional activation …

2005年10月12日 · Here we show that antibodies against mitotic chromosomal antigens that are associated with human autoimmune diseases 9 specifically recognize H3 molecules that are …

2020年10月14日 · One of them is the phosphorylation of serine 10 on histone H3 (H3S10ph). Main body: H3S10ph is emerging as an important player in the initiation and propagation of …

Our results indicate that H3S10P presents a remarkable distribution pattern in preimplantation mouse embryos until the 4-cell stage and is a better marker of pericentromeric …

2019年11月25日 · The chromosomal kinase JIL-1 is responsible for interphase histone H3S10 phosphorylation and has been proposed to protect active chromatin from heterochromatinisation.

Phosphorylation of histone H3 serine 10 (p-H3S10) is tightly associated with cell cycle progression; it also occurs when cells are exposed to certain environmental stresses or growth …

2013年11月21日 · Histone H3S10 plays a key role in maintaining genome stability, as scored by ectopic recombination and plasmid loss, Rad52 foci, and Rad53 checkpoint activation. …

H3S10ph broadly demarcates gene-rich regions in G1 and is positively correlated with domains of early DNA replication timing (RT) but negatively correlated with H3K9me2 and lamin …

2003年9月15日 · Phosphorylation of Ser10 in the tails of histone H3 has been extensively studied in many organisms. Interestingly, this modification is involved in both transcription and cell …