组蛋白修饰 | 一文带你了解H3K4me3 - 知乎 - 知乎专栏
H3K4me3是最重要的甲基化修饰之一，真核生物中该修饰在转录起始位点普遍发生，通常在基因的启动子附近富集，并且与基因的转录相关，是表观遗传学一个标志，其水平可以反映出转录的 …
H3K4me3 - Wikipedia
H3K4me3 is an epigenetic modification to the DNA packaging protein Histone H3 that indicates tri-methylation at the 4th lysine residue of the histone H3 protein and is often involved in the …
H3K4甲基化（H3K4me3）在生物学和疾病中的作用 - 简书
Jan 3, 2025 · H3K4me3的广泛区域（broad domains）是指基因组中H3K4me3与比典型的两个或三个核小体更大范围的区域相关，这些区域与持续的基因表达有关。广泛的H3K4me3区域存 …
H3K4me3 - 百度百科
H3K4me3，中文名组蛋白第三亚基四号赖氨酸的三甲基化，H3K4me3是指组蛋白第三亚基四号赖氨酸的三甲基化；一个特定的组蛋白赖氨酸甲基转移酶( HMT )，将三甲基团转移到组蛋白 3上。
组蛋白修饰 - Abcam中文官网
了解最常见的组蛋白修饰，例如 H3K4me3,H3K9me3 和 H3K27me3 以及其 readers, writers, 和 erasers。 下载完整表观遗传学应用指南
Nature：揭示H3K4me3在转录调控中的具体作用 - 知乎
在众多的组蛋白修饰中，基因活化状态的标志物组蛋白H3上第4位的赖氨酸三甲基化（ H3K4me3 ）是被研究得最为广泛的PTMs之一，在哺乳动物细胞中其可以被6种不同的 COMPASS复合 …
H3K4me3 regulates RNA polymerase II promoter-proximal pause …
Mar 1, 2023 · Our data show that H3K4me3 has a key role in regulating RNAPII pause-release; however, notably, we did not detect a role for H3K4me3 in regulating transcription initiation. …
Roles of H3K4 methylation in biology and disease - Cell Press
Jun 21, 2024 · Trimethylated H3 lysine 4 (H3K4me3) is one of the most studied histone modifications owing to its enrichment at the start sites of transcription and its association with …
Roles of H3K4 methylation in biology and disease - ScienceDirect
Feb 1, 2025 · In this review, we focus on recent studies that have yielded insights into how levels and patterns of H3K4me3 are regulated, how H3K4me3 contributes to the regulation of …
Roles of H3K4 methylation in biology and disease - PubMed
Jun 21, 2024 · Trimethylated H3 lysine 4 (H3K4me3) is one of the most studied histone modifications owing to its enrichment at the start sites of transcription and its association with …