Glucose-6-phosphatase, catalytic subunit (glucose 6-phosphatase alpha) is an enzyme that in humans is encoded by the G6PC gene. [5] [6] Glucose-6-phosphatase is an integral membrane protein of the endoplasmic reticulum that catalyzes the hydrolysis of D-glucose 6-phosphate to D-glucose and orthophosphate.

2024年12月25日 · Glucose-6-phosphatase (G6Pase) is a multi-subunit integral membrane protein of the endoplasmic reticulum that is composed of a catalytic subunit and transporters for G6P, inorganic phosphate, and glucose. This gene (G6PC) is one of the three glucose-6-phosphatase catalytic-subunit-encoding genes in human: G6PC, G6PC2 and G6PC3.

葡萄糖 6 磷酸酶 (g6pase) 是内质网的多亚基整合膜蛋白，由催化亚基和 g6p、无机磷酸盐和葡萄糖的转运蛋白组成。该基因 (g6pc) 是人类三种葡萄糖-6-磷酸酶催化亚基编码基因之一：g6pc、g6pc2 和 g6pc3。

6-磷酸葡萄糖的水解由 葡萄糖-6-磷酸酶 （g6pc）催化。此酶存在于肝和肾，其它组织没有。所以只有肝和肾可通过异生调节血糖。

Glucose-6-phosphatase (G6Pase) is a multi-subunit integral membrane protein of the endoplasmic reticulum that is composed of a catalytic subunit and transporters for G6P, inorganic phosphate, and glucose. This gene (G6PC) is one of the three glucose-6-phosphatase catalytic-subunit-encoding genes in human: G6PC, G6PC2 and G6PC3.

In this study, we summarize the reported G6PC mutations and review what mutagenesis studies have revealed about the structure and function of the G6PC catalytic unit. We also provide a summary table that unites the various nomenclatures used in the literature reporting mutations in G6PC in accordance with the guidelines of the Human Genome ...

The G6PC gene provides instructions for making an enzyme called glucose 6-phosphatase. This enzyme is found on the membrane of the endoplasmic reticulum, which is a structure inside cells that is involved in protein processing and transport.

葡萄糖-6-磷酸酶催化亚基 （g6pc）1 和 g6pc2 对葡萄糖代谢至关重要，可调节糖酵解、糖异生和糖原分解等过程。 尽管 G6PC1 和 G6PC2 在结构和功能上相似，但它们表现出不同的组织特异性表达模式、G6P 水解动力学和生理功能。

2009年10月23日 · It is a multicomponent system located in the endoplasmic reticulum that comprises several integral membrane proteins, namely a catalytic subunit (G6PC) and transporters for G6P, inorganic phosphate, and glucose. The G6PC gene family contains three members, designated G6PC, G6PC2, and G6PC3. The tissue-specific expression patterns of …

2025年2月8日 · This gene (G6PC) is one of the three glucose-6-phosphatase catalytic-subunit-encoding genes in human: G6PC, G6PC2 and G6PC3. Glucose-6-phosphatase catalyzes the hydrolysis of D-glucose 6-phosphate to D-glucose and orthophosphate and is a key enzyme in glucose homeostasis, functioning in gluconeogenesis and glycogenolysis.