2024年12月25日 · FZD10 (Frizzled Class Receptor 10) is a Protein Coding gene. Diseases associated with FZD10 include Fallopian Tube Serous Adenocarcinoma and Colorectal Cancer. Among its related pathways are ncRNAs involved in Wnt signaling in hepatocellular carcinoma and Alzheimer's disease and miRNA effects.

2024年4月17日 · Given the essential roles of FZD receptors in the Wnt signaling in human tumors, this review aims to consolidate the prevailing knowledge on the specific status of FZD receptors (FZD1–10)...

2025年2月8日 · [Exosomal FZD10 derived from non-small cell lung cancer cells promotes angiogenesis of human umbilical venous endothelial cells in vitro]. Targeting fatty acid synthase sensitizes human nasopharyngeal carcinoma cells to …

2024年12月28日 · By constructing a reliable 3D model of FZD10 and utilizing molecular docking and dynamics simulations, we identified several FDA-approved drugs with potential inhibitory effects on FZD10.

Here, we characterized FZD10 expression in the dorsal neural tube where it overlaps with both Wnt1 and Wnt3a, as well as markers of dorsal progenitors and interneurons. We show FZD10 expression is sensitive to Wnt1, but not Wnt3a expression, and FZD10 plays a …

2005年6月27日 · Genome-wide expression profiling revealed overexpression of the gene encoding frizzled homologue 10 (FZD10), a cell-surface receptor for molecules in the Wnt pathway, as a potential contributor...

2020年6月12日 · We show FZD10 expression is sensitive to Wnt1, but not Wnt3a expression, and FZD10 plays a role in neural tube patterning. Knockdown approaches show that Wnt1 induced ventral expansion of dorsal neural markes, Pax6 and Pax7, requires FZD10.

2022年7月21日 · Elevated FZD10 expression promotes liver cancer stem cell expansion and lenvatinib resistance, indicating that FZD10 expression is a novel prognostic biomarker and therapeutic target for human hepatocellular carcinoma.

2024年12月28日 · This study focuses on the potential of repurposed FDA-approved drugs targeting FZD10 as a therapeutic strategy for nasopharyngeal carcinoma (NPC). The tertiary structure of human FZD10 was constructed using homology modeling, validated by Ramachandran plot and ProQ analysis.

2019年7月25日 · FZD proteins, a family of receptors comprised in the Wnt signaling pathway, play an important role in carcinogenesis of the gastroenteric tract. Here, a still unknown role of Frizzled 10 (FZD10) protein was identified.