FK506-Binding Proteins and Their Diverse Functions - PMC
FK506 binding proteins (FKBPs) are a family of highly conserved proteins in eukaryotes. The prototype of this protein family, FKBP12, is the binding partner for immunosuppressive drugs …
FKBP Ligands—Where We Are and Where to Go? - PMC
2021年11月18日 · FK506-binding proteins (FKBPs) belong to the immunophilin family. Like other immunophilins many FKBPs possess a cis-trans peptidyl-prolyl isomerase (PPIase) activity. In …
Comparative analysis of FKBP family protein: evaluation, structure, …
Since FK506-binding proteins (FKBP) were first identified, much progress has been made in understanding the mechanisms involved in regulating the immunological process, steroid …
FKBP Ligands—Where We Are and Where to Go? - Frontiers
2018年12月5日 · FK506-binding proteins (FKBPs) belong to the immunophilin family. Like other immunophilins many FKBPs possess a cis-trans peptidyl-prolyl isomerase (PPIase) activity. In …
FKBP family proteins as promising new biomarkers for cancer
FK506-binding proteins (FKBPs) belong to the immunophilin family and bind immunosuppressive drugs, such as FK506 and rapamycin.
FKBP family proteins as promising new biomarkers for cancer
2011年8月1日 · FKBPs participate in cancer cellular processes. FKBPs are implicated in cell growth and survival and apoptotic signaling pathways. FKBP51 provide a relevant tissue …
FK506 binding proteins and inflammation related signalling ... - PubMed
FK506 binding (FKBP) proteins are part of the highly conserved immunophilin family and its members have fundamental roles in the regulation of signalling pathways involved in …
FKBP (FK506 Binding Protein) - SpringerLink
2018年1月1日 · FKBP (FK506 Binding Protein), Table 1 FKBP classification with synonyms of gene and protein. In the 1970s, after a decade from the purification of cyclosporine, a selective …
FKBP4 promotes glycolysis and hepatocellular carcinoma ... - Nature
2024年11月6日 · FKBP4, a member of the FK506-binding protein (FKBP) family, is a promising target for a variety of disorders, including cancer. However, its underlying molecular …
trigger-inducible split-Csy4 architecture for programmable RNA ...
2025年1月15日 · Here, we report a split-Csy4 architecture that was carefully optimized for in vivo usage. First, we separated Csy4 into two independent protein moieties whose full catalytic …