ELOVL1 Gene - GeneCards | ELOV1 Protein | ELOV1 Antibody
2024年12月24日 · ELOVL1 (ELOVL Fatty Acid Elongase 1) is a Protein Coding gene. Diseases associated with ELOVL1 include Ichthyotic Keratoderma, Spasticity, Hypomyelination, And …
A comprehensive review of the family of very-long-chain fatty acid ...
2023年11月20日 · The family of very-long-chain fatty acid elongases (ELOVL1-ELOVL7) plays a crucial role in cellular metabolism by facilitating the elongation of fatty acids beyond the typical …
Therapeutic Role of ELOVL in Neurological Diseases - PMC
Seven elongases, ELOVL1–7, have been identified in mammals and each has a unique substrate specificity. Researchers have recently developed a keen interest in the elongation of very long …
ELOVL1 ELOVL fatty acid elongase 1 [ (human)] - National Center …
2025年2月9日 · ELOV1 promotes very long-chain fatty acid accumulation X-linked adrenoleukodystrophy and is inhibited by CoA esters of bezafibrate and gemfibrozil. Results …
Enzymatic characterization of ELOVL1, a key enzyme in very long …
2015年2月1日 · ELOVL1 is the key enzyme in the elongation of C22:0 to C26:0 and to study it at the enzyme level, we generated an ELOVL1 over-expression model using HEK293 Flp-In …
Therapeutic Role of ELOVL in Neurological Diseases | ACS Omega
2023年3月8日 · Seven elongases, ELOVL1–7, have been identified in mammals and each has a unique substrate specificity. Researchers have recently developed a keen interest in the …
A functional single-cell metabolic survey identifies Elovl1 as a …
2025年3月10日 · Elovl1-deficient T cells increased mitochondrial fitness and fatty acid oxidation, thus withstanding the metabolic stress imposed by the tumour microenvironment. Finally, …
The structural basis of fatty acid elongation by the ELOVL ... - Nature
2021年6月10日 · To understand the molecular basis of acyl chain elongation by the ELOVL elongases, we purified and solved the crystal structure of human ELOVL7 in complex with a …
ELOVL1 production of C24 acyl-CoAs is linked to C24 sphingolipid ...
2010年10月26日 · Particularly notable was the high activity exhibited by ELOVL1 toward saturated and monounsaturated C20- and C22-CoAs, and that it was essential for the …
ELOVL1 ELOVL fatty acid elongase 1 [ Homo sapiens (human) ]
2024年3月5日 · Title: Dominant ELOVL1 mutation causes neurological disorder with ichthyotic keratoderma, spasticity, hypomyelination and dysmorphic features. ELOV1 promotes very long …
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