Erythroid Krüppel-like factor (EKLF or KLF1) is a transcriptional regulator that plays a critical role in lineage-restricted control of gene expression. KLF1 expression and activity are tightly …

目的 红细胞 Kruppel 样因子 (EKLF) 是 β 型珠蛋白基因转换的必需转录因子，并且特异性激活成人 β 珠蛋白基因启动子的转录。 我们试图确定 EKLF 是否也需要短链脂肪酸 (SCFA) 衍生物激活 γ …

EKLF/Klf1 is a zinc-finger transcription activator essential for erythroid lineage commitment and terminal dif-ferentiation. Using ChIP-seq, we investigate EKLF DNA binding and transcription …

Erythroid Krüppel-like factor (EKLF) is an erythroid cell-specific DNA-binding protein that activates transcription from the beta-globin CACCC element, a functionally important and evolutionarily …

Nov 5, 2021 · EKLF/Klf1 is a master transcriptional activator of critical genes that regulate both erythroid fate specification and terminal erythroid maturation.

Dec 20, 2022 · EKLF/Klf1 is a zinc-finger transcription activator essential for erythroid lineage commitment and terminal differentiation. Using ChIP-seq, we investigate EKLF DNA binding …

Erythroid Krüppel-like factor (ELKF/KLF1) 1 is the founding member of the Krüppel-like factor (KLF) family that comprises 17 different transcription factors playing critical roles in diverse …

Apr 4, 2015 · Erythroid Kruppel-like factor (EKLF or KLF1) is a transcription factor crucial for red cell development that is directly involved in regulation of a large number of erythroid genes. …

May 4, 2012 · EKLF activates transcription of E2f2, through which it regulates the entry of erythroid progenitors into the cell divisions that precede terminal erythroid differentiation (17, …

Apr 13, 2006 · EKLF is an erythroid-specific, zinc finger-containing transcription factor essential for the activation of the mammalian beta globin gene in erythroid cells of definitive lineage.