EFNB2 Gene - GeneCards | EFNB2 Protein | EFNB2 Antibody
2024年12月24日 · EFNB2 (Ephrin B2) is a Protein Coding gene. Diseases associated with EFNB2 include Cholestasis, Benign Recurrent Intrahepatic, 2 and Kaposi Sarcoma. Among its related pathways are EPH-Ephrin signaling and EphB-EphrinB Signaling. Gene Ontology (GO) annotations related to this gene include signaling receptor binding and ephrin receptor binding.
Ephrin B2 - Wikipedia
Ephrin-B2 is a protein that in humans is encoded by the EFNB2 gene. [5] This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis.
1948 - Gene ResultEFNB2 ephrin B2 [ (human)] - National Center …
EfnB2 is an essential regulator of endothelial cell death and vessel pruning. This regulation depends upon phosphotyrosine-EfnB2 signaling repressing JNK3 activity via STAT1. Results suggest that ephrinB2 may function as a colorectal cancer cells growth stimulator.
EFNB2 ephrin B2 - NIH Genetic Testing Registry (GTR) - NCBI
2024年12月10日 · Clinical resource with information about EFNB2, and available tests. There are links to practice guidelines and authoritative resources like GeneReviews, PubMed, MedlinePlus, PharmGKB and clinicaltrials.gov.
肝配蛋白 B2（EFNB2）基因 | MCE - MCE-生物活性分子大师
基于它们的结构和序列关系，肝配蛋白分为肝配蛋白-A (EFNA) 类和肝配蛋白 B (EFNB) 类，前者通过糖基磷脂酰肌醇键固定在膜上，后者是跨膜蛋白。 该基因编码与 EphB4 和 EphA3 受体结合的 EFNB 类肝配蛋白。 [RefSeq 提供，2008 年 7 月] This gene encodes a member of …
Targeting Forward and Reverse EphB4/EFNB2 Signaling by a
2020年1月16日 · Trans-interaction between EphB4 and its membrane-bound ligand ephrin B2 (EFNB2) mediates bi-directional signaling: forward EFNB2-to-EphB4 signaling suppresses tumor cell proliferation, while...
EFNB2 facilitates cell proliferation, migration, and invasion in ...
The down-regulation of EFNB2 inhibited cell proliferation by up-regulating p53/p21-mediated G0/G1 phase blockade. Knockdown of EFNB2 decreased the migration and invasion of PDAC cells by blocking epithelial-mesenchymal transition.
EFNB2 - an overview | ScienceDirect Topics
Human ephrinB2 is a transmembrane protein encoded by the EFNB2 gene. EphrinB2 has one transmembrane domain, a receptor-binding domain (RBD) on the extracellular side, and a PDZ domain on the intracellular side.
Ephrin-B2 controls VEGF-induced angiogenesis and …
2010年5月27日 · Here we show with genetic experiments in mouse and zebrafish that ephrin-B2, a transmembrane ligand for Eph receptor tyrosine kinases, promotes sprouting behaviour and motility in the angiogenic...
STTT丨缺血性心脏病治疗新靶点EphrinB2医药新闻-ByDrug-一站式 …
2025年1月21日 · 通过流式分选以及免疫荧光染色实验发现，Efnb2过表达还改善了MI后心脏损伤局部的巨噬细胞浸润，促进了纵隔淋巴结回流的巨噬细胞增多。综上所述，EphrinB2过表达可促进MI后心肌淋巴管生成，减轻心肌炎症，改善心脏功能。