Thermo Scientific DNase I, RNase-free is an endonuclease that digests single- and double-stranded DNA. It hydrolyzes phosphodiester bonds producing mono- and oligodeoxyribonucleotides with 5'-phosphate and 3'-OH groups.

DNase I (Deoxyribonuclease I) digests single- and double-stranded DNA to oligodeoxyribonucleotides containing a 5' phosphate. Ribonuclease has been reduced to non-detectable levels. DNase I is suitable for removing DNA from protein preparations, nick translating DNA, and generating random fragments for dideoxy sequencing.

Thermo Scientific DNase I removes unwanted DNA from cell lysates to improve protein extraction efficiency. Features of RNase-free DNase I: • Degrades and removes unwanted DNA from samples • Cleaves both single-stranded and double-stranded DNA • Compatible with Thermo Scientific Pierce Cell Lysis Reagents

DNase I is an endonuclease that hydrolyzes phosphodiester linkages yielding oligonucleotides with a 5'-phosphate and a 3'-hydroxyl group (Kunitz, 1950). DNase I has been shown to act on single- and double-stranded DNA, chromatin, and RNA:DNA hybrids.

DNase I iis an endonuclease that digests single- and double-stranded DNA. It hydrolyzes phosphodiester bonds producing mono- and oligodeoxyribonucleotides with 5’-phosphate and 3’-OH groups.

Thermo Scientific DNase I removes unwanted DNA from cell lysates to improve protein extraction efficiency. Features of RNase-free DNase I: Degrades and removes unwanted DNA

DNase I, Amplification Grade digests single- and double-stranded DNA to oligodexyribonuleotides. The specific activity is 10,000 units/mg. DNase I, Amplification Grade is purified and tested for non-detectable levels of RNase contamination.

DNase I is suitable for removing DNA from protein preparations, nick translating DNA, and generating random fragments for dideoxy sequencing. DNase I is purified from bovine pancreas. The specific activity of DNase I is typically in the range of 10,000–25,000 units/mg.

Thermo ScientificTM DNase I is commonly used to degrade unwanted single- and double-stranded DNA into 5 ́ phosphodinucleotide and oligonucleotide fragments.1 The properties of DNase I can be modified by divalent ions.

Thermo Scientific DNase I, RNase-free is an endonuclease that digests single- and double-stranded DNA. It hydrolyzes phosphodiester bonds producing mono- and oligodeoxyribonucleotides with 5'-phosphate and 3'-OH groups.