dnaQ is the gene encoding the ε subunit of DNA polymerase III in Escherichia coli. [1] The ε subunit is one of three core proteins in the DNA polymerase complex. It functions as a 3’→5’ …

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The Escherichia coli dnaQ gene encodes the 3′→5′ exonucleolytic proofreading (ɛ) subunit of DNA polymerase III (Pol III). Genetic analysis of dnaQ mutants has suggested that ɛ might …

Sep 11, 2023 · Here, we characterized the spacer acquisition of the adaptation module of the Streptococcus thermophilus type I-E system, in which a DnaQ domain naturally fuses with …

May 1, 2002 · In this review, we first discuss the proofreading functions of 3′–5′ exonucleases, and then describe the more recently discovered enzymes with 3′–5′ exonuclease activity, the …

Apr 15, 2015 · The dnaQ gene of Escherichia coli encodes the ε subunit of DNA polymerase III, which provides the 3′ → 5′ exonuclease proofreading activity of the replicative polymerase. …

Oct 15, 1999 · Here we report the discovery and characterization of a new E. coli exonuclease, exonuclease X. Exonuclease X is a member of a superfamily of proteins that have homology …

Oct 24, 2023 · We demonstrated that mycobacterial DnaQ binds to the b-clamp and functions synergistically with the PHP domain to correct replication errors. Further, we found that the …

Apr 2, 1996 · The Escherichia coli dnaQ gene encodes the proofreading 3' exonuclease (epsilon subunit) of DNA polymerase III holoenzyme and is a critical determinant of chromosomal …

The nucleotide sequences of the recessive dnaQ49 and the dominant mutD5 mutator were determined. The dnaQ49 mutator has a single base substitution in the dnaQ gene, thus …