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Due to the large number of users, DINC cannot be provided with as much computing power on this server as our most advanced experiments require to obtain good results. By providing DINC with more computing resources, the accuracy of docking results can be improved.

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To deal with this issue and perform molecular docking of large ligands, the Kavraki Lab at Rice University has developed DINC (Docking INCrementally). DINC uses an incremental algorithm to efficiently explore the search space of potential binding modes between a ligand and a protein.

Here we describe DINC 2.0, a revamped version of the DINC webserver with enhanced capabilities and a more user-friendly interface. DINC 2.0 allows docking ligands that were previously too challenging for DINC, such as peptides with more than 25 flexible bonds.

2013年11月8日 · In our earlier work, we presented a novel AutoDock-based incremental protocol (DINC) that addresses the limitations of AutoDock's standard protocol by enabling improved docking of large ligands.

2006年3月28日 · Two adults married or non-married living together, both working jobs. Only supporting themselves, or being without children. In other words, Double Income No Children or DINC. Get the DINC mug. Kind of like a dunce, but dunce-ier. "Wow, he's so busy hanging out with his girlfriend that he won't even talk to us." "Yeah, dince alert."

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DINC is a slang term that refers to people who are "double income, no children." These individuals are typically married or in long-term relationships and have two sources of income but do not have any children. The term has become popular in recent years as more and more couples are choosing to delay having children or not have them at all.

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