DAX1 (dosage-sensitive sex reversal, adrenal hypoplasia critical region, on chromosome X, gene 1) is a nuclear receptor protein that in humans is encoded by the NR0B1 gene (nuclear …

The NR0B1 gene provides instructions for making a protein called DAX1. Learn about this gene and related health conditions.

DAX1 was initially identified as part of a contiguous gene syndrome and is known to function in the proper formation of the adult adrenal gland. It has been hypothesized that DAX1 is …

DAX1 (locus: Xp21.2) encodes a nuclear receptor required for testis, ovary, adrenal, and gonadotroph differentiation. DAX1 duplications result in dosage-sensitive sex reversal by …

DAX-1 (NR0B1) and SF-1 (NR5A1) are two nuclear receptor transcription factors that play a key role in human adrenal and reproductive development. Loss of DAX-1 function is classically …

DAX1 (NR0B1) is a nuclear receptor with a characteristic C-terminal ligand binding domain, but an atypical DNA binding domain. Mutations in the DAX1 gene cause adrenal hypoplasia …

2016年9月22日 · The DAX1 gene encodes a deduced 470-amino acid protein that belongs to the nuclear hormone receptor superfamily and displays a novel DNA-binding domain at the N …

DAX1 (dosage-sensitive sex reversal, adrenal hypoplasia critical region, on chromosome X, gene 1; also known as NROB1, nuclear receptor subfamily 0, group B, member 1) encodes a …

2005年9月1日 · Here, we review DAX1/Dax1 known functional roles and the recently hypothesized function in the development of the embryo and in the maintenance of embryonic …

2023年5月29日 · Here the authors report that estrogen receptor alpha (ERα) interacts with the genome and the nuclear receptor co-repressor NR0B1 (DAX1) to manifest region-specific …