DLD-1 is a colorectal adenocarcinoma cell line isolated from the large intestine of a colon adenocarcinoma patient and can be used in cancer research. Discounts may be available for our fellow nonprofit organizations. Login to see your price. Generally ships within 1-3 business days.

DLD-1 is a human colorectal carcinoma cell line commonly employed in cancer research. It is a valuable tool for investigating various aspects of colon cancer, including tumour development, progression, underlying molecular mechanisms, and response to therapeutic agents.

Feasibility of drug screening with panels of human tumor cell lines using a microculture tetrazolium assay.

Senescence in the cancer cell line DLD-1 is activated by DDW. It was investigated whether maintaining the cells in DDW was able to induce senescence in the DLD-1 cell line, and therefore offer a novel platform for cancer therapeutics.

DLD-1 cells are used to create the xenograft mouse model that enables studies on anti-EGFR therapeutics, such as IMC-C225, in combination with other conventional chemotherapies.

The COLO201 and DLD-1 cell lines were used to measure the reduced glutathione (GSH) and oxidized glutathione (GSSG) ratio after pharmacological inhibition of mTOR. In COLO201, INK128 was found to decrease the GSH/GSSG ratio, but in DLD-1, a …

The DLD-1 cell line was established in 1979 from the epithelial tumorigenic tissue of a Dukes’ type C tumor of an adult male patient with colorectal adenocarcinoma. DLD-1 is positive for myc, myb, ras, fos, sis, and p53 oncogenes and negative for ABL, ROS, and SRC oncogenes.

2 days ago · Identifying antigens that elicit protective immunity is pivotal for developing effective vaccines and therapeutics against cutaneous leishmaniasis. Dihydrolipoyl dehydrogenase (DLD), a mitochondrial enzyme involved in oxidizing lipoamides to facilitate electron transfer for energy production and met …

Jan 5, 2022 · Cell information for DLD-1. Find diseases associated with this biological target and compounds tested against it in bioassay experiments.

DLD-1 cells, a cell line derived from human colorectal cancer, display epithelial properties such as a cobblestone cell shape. We introduced a control vector encoding DsRed or an expression vector encoding HA-tagged Snail1 protein into DLD-1 cells and isolated stable transfectants, designated DsRed+ or Snail+ cells, respectively.