2024年12月24日 · CXCL17 (C-X-C Motif Chemokine Ligand 17) is a Protein Coding gene. Diseases associated with CXCL17 include Cholera. Among its related pathways are Chemokine Superfamily: Human/Mouse Ligand-Receptor Interactions and …

Chemokine (C-X-C motif) ligand 17 (CXCL17) is a small cytokine belonging to the CXC chemokine family that has been identified in humans and mice. CXCL17 attracts dendritic cells and monocytes and is regulated in tumors. It is also known as VEGF co-regulated chemokine 1 (VCC-1) and dendritic cell- and monocyte-attracting chemokine-like protein ...

2024年5月29日 · CXCL17, a novel member of the CXC chemokine class, has been implicated in several human pathologies, but its role in mediating immune response is not well understood. Characteristic features of immune response include resident macrophages orchestrating successive and structured recruitment of neutro …

2020年6月1日 · CXCL17, a myeloid cell-attracting chemokine, also known as dendritic cell and monocyte-like protein (DMC) or VEGF co-regulated chemokine 1 (VCC-1), is the newest member of the CXCL family of chemotactic cytokines described so far [18].

2013年1月1日 · The mature CXCL17 exhibited strong chemoattractant abilities targeting monocytes and macrophages, potentially through ERK1/2 and p38 but not JNK signaling. CXCL17 also induced the production of proangiogenic factors such as vascular endothelial growth factor A from treated monocytes.

cxc配体17（cxcl17）是一种新型的cxc趋化因子，其临床意义仍未知。本篇研究中，作者分析了cxcl17对肝癌（hcc）患者的预后价值，并评估了cxcl17与免疫浸润的关系。

2024年3月19日 · CXCL17 is a chemokine principally expressed by mucosal tissues, where it facilitates chemotaxis of monocytes, dendritic cells, and macrophages and has antimicrobial properties. CXCL17 is also implicated in the pathology of inflammatory disorders and progression of several cancers, and its expression is increased during viral infections of the lung.

2025年2月8日 · CXCL17 increases MDSCs PDGF-BB secretion which contributes to MDSC-mediated angiogenesis in the lung metastatic niche and colonization of breast cancer. Patients with high levels of CXCL17 have shorter distant metastasis-free and overall survival rates.

2024年3月19日 · cxcl17 是一种主要由粘膜组织表达的趋化因子，可促进单核细胞、树突状细胞和巨噬细胞的趋化性，并具有抗菌特性。 CXCL17 还与炎症性疾病的病理学和几种癌症的进展有关，并且在肺部病毒感染期间其表达增加。

2020年9月1日 · CXCL17, the last described chemokine, has recently been found to be abundantly and specifically expressed in mucosal sites, while its receptor is still not well determined. Accumulative studies indicate that CXCL17 could potentially exhibit chemotactic, anti-inflammatory, antimicrobial activities under multiple biological conditions.