Question: CO2Et EtO2C CO2Et NaOET EtOH CO2Et The Michael reaction is a conjugate addition process wherein a nucleophilic enolate anion (the donor) reacts with an a,B-unsaturated carbonyl compound (the acceptor).

OH Ph3P=O Ph3P Ph CH3 NS Ph .CO2Et + OH CH3 H3C EtO2C H3C1 CO2Et EtO2C The Fischer esterification reaction synthesizes an ester via a nucleophilic acyl substitution reaction. The stereochemistry of the alcohol group is unchanged as it is the alcohol oxygen that makes the nucleophilic attack.

1. NaOEt 3. heat CO2H+ CO2 EtOH H3C CO2Et The malonic ester synthesis is a carbonyl alkylation reaction. It is used to prepare carboxylic acids from primary alkyl halides, lengthening the carbon chain by two atoms. Thus, the product can …

What is the missing reagent? CO2H CO2Et 1) NaOH 2)? A) EtOH B) EtMgBr C) EtBI D) CH=CH2 A. A OB.B OC.C ODD

Question: a- CO2Et he above reaction represents an alkylation via an enamine. Draw the structure of the enamine and the alkyl chloride that were used to produce the product. Use pyrrolidine as the secondary amine. • Do not consider stereochemistry in your drawing, even though stereochemistry may be indicated in the reaction.

OH CH CO2Et Nat OET Ethanol, 250 CH3CHO + CH3 CH3CHCO2CH2CH3 H₃c- H3C CH3 Ethyl 3-hydroxy-2,2-dimethylbutanoacetate reacts instantly at room temperature when treated with ethoxide ion to yield two products, acetaldehyde and ethyl 2-methylpropanoate. Draw curved arrows to show the movement of electrons in this step of the reaction mechanism.

22.86 Predict the major product for each of the following transformations: Eto C CO2Et Heat Eto2C co2Et CH2CO Et 1) NaOEt C11H103 H2CO2Et Hao* Heat C8H120 8 12 Your solution’s ready to go! Our expert help has broken down your problem into …

CO.Et 1. NaOEt 2. H307 3. heat Hac + Br COH + CO2 + EtOH Нас CO2Et The malonic ester synthesis is a carbonyl alkylation reaction. It is used to prepare carboxylic acids from primary alkyl halides, lengthening the carbon chain by two atoms. Thus, the product can be visualized as being a "substituted acetic acid."

Which is the main product of the following reaction? 1) NaOEt, EtOH OEt EtO 2) H3O+ CO2Et CO2Et 36

Question: o CH3 CO2Et Hagemann's ester The compound known as Hagemann's ester is prepared by treatment of a mixture of formaldehyde and ethyl acetoacetate with base, followed by acid-catalyzed decarboxylation. The reaction involves the following steps: 1. Deprotonation of ethyl acetoacetate to form enolate ion 1; 2.