CDC6 - Wikipedia
Cell division control protein 6 homolog is a protein that in humans is encoded by the CDC6 gene. [5] [6] The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a …
Molecular Cancer︱山东大学齐鲁医院等团队揭示CDC6蛋白的去泛 …
细胞分裂周期蛋白6（CDC6）在DNA复制过程中发挥重要作用。作为前复制复合物（pre-RC）中的核心成员，如果CDC6发生突变或缺失，pre-RC将无法组装，DNA复制也会受到抑制。由 …
CDC6 Gene - GeneCards | CDC6 Protein | CDC6 Antibody
Dec 24, 2024 · CDC6 (Cell Division Cycle 6) is a Protein Coding gene. Diseases associated with CDC6 include Meier-Gorlin Syndrome 5 and Meier-Gorlin Syndrome 1. Among its related …
所有肿瘤都会发生异常的通路——Cell cycle信号通路（二） - 知乎
用生长促进因子刺激细胞导致cyclinD (包括D1、D2和D3三种同源蛋白）上调，其激活CDK4和CDK6。 在经典的细胞周期模型中，CyclinD-CDK4/6复合物与cyclinE（包括E1和E2两种同源 …
CDC6: from DNA replication to cell cycle checkpoints and …
Nov 28, 2007 · Cell division cycle 6 (CDC6) is an essential regulator of DNA replication in eukaryotic cells. Its best-characterized function is the assembly of prereplicative complexes at …
The structure of ORC–Cdc6 on an origin DNA reveals the …
Jun 23, 2021 · Here we report the cryo-EM structure at 3.3 Å resolution of the yeast ORC–Cdc6 bound to an 85-bp ARS1 origin DNA. The structure reveals that Cdc6 contributes to origin …
周期蛋白6在DNA复制、细胞周期检测点和肿瘤发生发展中的作用
周期蛋白6 (CDC6)是组成前复制复合物 (Pre-RC)的主要蛋白之一,控制细胞从G1期进入S期,同时也参与激活和维持有丝分裂S-M期检测点机制.最近的研究发现其也具有原癌基因的特性,并在人 …
Cdc6 disruption leads to centrosome abnormalities and …
Oct 5, 2020 · Cell division cycle 6 (Cdc6) plays key roles in regulating DNA replication, and activation and maintenance of cell cycle check points. In addition, Cdc6 exerts oncogenic...
细胞分裂周期 6（CDC6）基因 | MCE - MCE-生物活性分子大师
The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early …
CDC6 gene - MedlinePlus
The CDC6 gene provides instructions for making a protein that is important in the copying of a cell's DNA before the cell divides (a process known as DNA replication). The protein produced …