CDC20 Gene - GeneCards | CDC20 Protein | CDC20 Antibody
2024年12月24日 · CDC20 (Cell Division Cycle 20) is a Protein Coding gene. Diseases associated with CDC20 include Oocyte/Zygote/Embryo Maturation Arrest 14 and Infertility. Among its …
Functional analysis of Cdc20 reveals a critical role of CRY box in ...
2024年2月9日 · As an essential regulator, Cdc20 promotes mitotic exit through activating APC/C and monitors kinetochore-microtubule attachment through activating SAC. Cdc20 requires …
Targeting Cdc20 as a novel cancer therapeutic strategy - PMC
2023年4月4日 · Emerging evidence has begun to reveal that Cdc20 and Cdh1 have opposing functions in tumorigenesis. Specifically, Cdh1 functions largely as a tumor suppressor, …
CDC20 in and out of mitosis: a prognostic factor and therapeutic …
2022年4月30日 · Cell division cycle 20 homologue (CDC20) is a well-known regulator of cell cycle, as it controls the correct segregation of chromosomes during mitosis.
The potential role of CDC20 in tumorigenesis, cancer progression …
Many studies have suggested that dysregulation of CDC20 is associated with various pathological processes in malignant solid tumors, including tumorigenesis, progression, chemoradiotherapy …
Cdc20: At the Crossroads between Chromosome Segregation and …
Cdc20 is the target of the spindle assembly checkpoint (SAC) and a key cofactor of the anaphase-promoting complex or cyclosome (APC/C) E3 ubiquitin ligase, thus regulating APC/C ubiquitin …
Cdc20: a potential novel therapeutic target for cancer treatment
In this review, we will discuss the physiological role of Cdc20 and its downstream substrates in vitro and in the transgenic mouse model reminiscent of the pathogenesis of human cancers.
Alternative CDC20 translational isoforms tune mitotic arrest duration
2023年4月26日 · CDC20 is a critical co-activator of the anaphase-promoting complex (APC/C; also known as the cyclosome)—an E3 ubiquitin ligase that directs the ubiquitination and …
Cdc20: A WD40 Activator for a Cell Cycle Degradation Machine
2007年7月6日 · Cdc20 is an essential cell-cycle regulator required for the completion of mitosis in organisms from yeast to man and contains at its C terminus a WD40 repeat domain that …
CDC20 in and out of mitosis: a prognostic factor and ... - PubMed
2022年4月30日 · Cell division cycle 20 homologue (CDC20) is a well-known regulator of cell cycle, as it controls the correct segregation of chromosomes during mitosis.
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