
CD44 Gene - GeneCards | CD44 Protein | CD44 Antibody
2024年12月24日 · CD44 (CD44 Molecule (IN Blood Group)) is a Protein Coding gene. Diseases associated with CD44 include Hematologic Cancer and Pleural Mesothelioma. Among its …
The biology and role of CD44 in cancer progression: therapeutic ...
Here, we review current data on the structural and functional properties of CD44, the known roles for CD44 in tumorigencity, the regulation of CD44 expression, and the potential for targeting …
CD44 - an overview | ScienceDirect Topics
CD44 is a widely distributed transmembrane cell adhesion molecule that is probably the most well-characterized receptor for HA (Aruffo et al., 1990). CD44–HA interaction is involved in …
CD44: structure, function, and association with the malignant
CD44 is a ubiquitous multistructural and multifunctional cells surface adhesion molecule involved in cell-cell and cell-matrix interactions. Twenty exons are involved in the genomic organization …
CD44: From adhesion molecules to signalling regulators
2003年1月1日 · CD44 and its associated partner proteins monitor changes in the extracellular matrix that influence cell growth, survival and differentiation.
CD44: A Multifunctional Mediator of Cancer Progression - PMC
CD44, a non-kinase cell surface transmembrane glycoprotein, has been widely implicated as a cancer stem cell (CSC) marker in several cancers. Cells overexpressing CD44 possess …
CD44: A Multifunctional Cell Surface Adhesion Receptor Is a ... - PubMed
2017年3月7日 · CD44 is a cell surface adhesion receptor that is highly expressed in many cancers and regulates metastasis via recruitment of CD44 to the cell surface. Its interaction …
The role of CD44 in disease pathophysiology and targeted treatment
CD44 has been implicated in a number of diseases such as cancer, arthritis, interstitial lung disease (ILD), vascular disease, wound healing, and infections by pathogens. CD44–HA …
Frontiers | CD44: molecular interactions, signaling and functions in ...
2015年5月6日 · CD44 is the major surface hyaluronan (HA) receptor implicated in intercellular and cell-matrix adhesion, cell migration and signaling. It is a transmembrane, highly …
CD44 as a tumor biomarker and therapeutic target
2020年12月10日 · In this review, we focus on current data relevant to CD44, and outline CD44 structure, the regulation of CD44, functional properties of CD44 in carcinogenesis and cancer …
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