2023年5月18日 · CD38 expression on CD8+ T cells is associated with risk of progression of HIV infection to AIDS, is associated with poor prognosis and may be used as surrogate marker for HIV RNA viral load (J Acquir Immune Defic Syndr Hum Retrovirol 1997;16:83, Cytometry B Clin Cytom 2009;76:375, J Acquir Immune Defic Syndr 2006;41:416)

2024年6月13日 · Plasma cells. CD138 is a useful marker of plasma cells and can help support a diagnosis of multiple myeloma. Answers B, C and D are incorrect because CD138 is not a useful marker in identifying T or B cells. While B cells may express CD138 during earlier stages of development, they lose expression of this marker at maturity.

2021年5月24日 · Bright CD38 expression that can be seen by flow cytometry in MYC rearranged B cell lymphomas (Leuk Lymphoma 2014;55:2592, Cytometry B Clin Cytom 2020;98:412) Flow cytometry images Contributed by Saja Asakrah, M.D.

2022年5月26日 · Express CD38, CD138, often CD56+ or CD117+; may have partial CD45, usually negative for CD20, CD19 and CD10 (Cytometry B Clin Cytom 2016;90:61) Exception in myeloma with t(11:14) where plasma cells more often …

2023年1月17日 · CD10 in diffuse large B cell lymphoma is a marker for germinal center phenotype (also HGAL, BCL6, CD38, LMO2), generally considered a favorable prognostic factor, secondary in part to association with cell of origin classification (germinal center B cell versus activated B cell) (Mod Pathol 2005;18:1113, J Hematop 2009;2:187)

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2023年4月13日 · CD38 is expressed at low levels on red blood cells (RBCs) See Laboratory for blood bank serologic testing issues related to CD38 expression on RBCs Anti-CD47 (magrolimab - Hu5F9-G4) (Pathology 2021;53:427): CD47 is widely expressed in the human body and acts as an antiphagocytic "do not eat me" marker on healthy cells

2023年2月9日 · Marker of NK cells and NK lymphomas Detects residual myeloma and residual acute myeloid leukemia in bone marrow ( Am J Clin Pathol 2009;132:60 , Am J Clin Pathol 2008;129:934 ) Differentiates plasma cells in myeloma (CD56+) from reactive plasmacytosis or monoclonal gammopathy of undetermined significance (MGUS) (CD56-) ( Am J Pathol …

2024年8月27日 · Positive: IgM, CD19, CD20, CD22, CD79a, CD25 and CD38 frequent expression Negative: CD5, CD10, CD103, CD23; however, CD23 expression is not uncommon in some cases CD5 and CD10 positive but BCL6 negative in a minority of cases Plasma cells in lymphoplasmacytic lymphoma Positive: CD138, CD19, CD45 and sometimes MUM1 but can …

2024年9月18日 · ALK expression does not support the diagnosis of DLBCL, NOS (answer B). It is, however, a defining feature of the ALK+ large B cell lymphoma, which is also characteristically CD20 negative. TdT is an immaturity marker characteristically expressed in acute lymphoblastic leukemia (answer C).