Complement receptor type 1 (CR1) also known as C3b/C4b receptor or CD35 (cluster of differentiation 35) is a protein that in humans is encoded by the CR1 gene. [3] [4] This gene is a member of the regulators of complement activation (RCA) family and is located in the 'cluster RCA' region of chromosome 1.

2024年12月24日 · CR1 (Complement C3b/C4b Receptor 1 (Knops Blood Group)) is a Protein Coding gene. Diseases associated with CR1 include Malaria and Follicular Dendritic Cell Sarcoma. Among its related pathways are Complement cascade …

2002年3月15日 · In the present study, we aimed to elucidate the role of human complement receptor type 1 (CR1), the other C3-receptor on B cells. As ligand, aggregated C3 and aggregated C3 (H 2 O), i.e., multimeric “C3b-like C3”, are used, which bind to CR1, but not to CR2.

2019年11月21日 · Complement receptor 1 (CR1, CD35), which is responsible for the Knops blood group on erythrocytes (York and McCoy antigens), is also expressed by antigen-presenting cells. This regulates the complement system by removing opsonized antigens, blocking the final steps of the complement cascade.

Our CD35 monoclonal, recombinant monoclonal and polyclonal antibodies are developed in Mouse, Rabbit and Rat. These antibodies have been verified by Relative expression to confirm specificity to CD35. Find the CD35 antibody that fits your needs.

CD35 (cluster of differentiation 35) stains the membrane and cytoplasm of follicular dendritic cells and granulocytes. Follicular dendritic cells form a basketweave meshwork in the germinal centers of lymphoid follicles, where they present antigens to B cells. CD35 is useful in the diagnosis of follicular dendritic-cell sarcoma.

2024年4月2日 · CD35, also known as complement receptor 1 (CR1), plays a crucial role in the complement system. The complement system is part of the immune system that recognizes and removes pathogens, promotes inflammatory responses, and regulates immune function through a series of cascading reactions.

1998年2月15日 · We show here that cross-linking of mouse CD21 (complement receptor type 2, CR2, C3d receptor) and CD35 (complement receptor type 1, CR1, C3b/C4b receptor) or co-cross-linking of CD21/CD35 and surface IgM rapidly up-regulates both B7-1 and B7-2 expression on murine resting splenic B cells.

CD35, also known as complement receptor 1 (CR1), is a protein found on the surface of various immune cells that plays a vital role in the immune response by facilitating the clearance of immune complexes and pathogens.

a type I transmembrane protein present on monocytes, granulocytes, dendritic cells, red blood cells, some T cells, and glomerular podocytes that facilitates phagocytosis and/or binding of immune complexes; expressed in Wilms tumor. Want to thank TFD for its existence?