Integrin beta-1 (ITGB1), also known as CD29, is a cell surface receptor that in humans is encoded by the ITGB1 gene. [5] This integrin associates with integrin alpha 1 and integrin alpha 2 to form integrin complexes which function as collagen receptors .

CD29 is widely expressed in human salivary glands and, it could serve as a potential biomarker for devising novel cellular therapeutic and diagnostic strategies for salivary gland disorders and malignancies. Keywords: Adult, CD29, fetal, progenitor, salivary gland, stem cells. Introduction

CD29 is widely expressed in human salivary glands, and it could serve as a potential biomarker for devising novel cellular therapeutic and diagnostic strategies for salivary gland disorders and malignancies.

2020年3月11日 · CD29 gene signature is associated with better survival, and CD29 + T cells are superior in killing tumor cells. (A and B) Kaplan–Meier plots of overall survival of (A) all patients suffering from SKCM or (B) of patients with high CD8 + T cell infiltrate estimates.

Recent evidence suggests that CD29 is an upstream regulator of Actopaxin, and their expressions in HCC are significantly positively correlated, moreover, there is a close relationship between the expression level of Actopaxin and the activity and phosphorylation of CD29 (Ng et al., 2013). Specifically, HCC cells with higher expression of CD29 ...

2020年3月24日 · Preselecting CD29-expressing MART1 TCR-engineered T cells potentiated the killing of target cells. We therefore propose that CD29 expression can help evaluate and select for potent therapeutic T cell products.

CD29 is an integrin unit associated with very late antigen receptors. Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals.

2023年3月28日 · Using human embryonic stem cell-derived retinal organoids, we investigated the transcriptomic profiles of CD29+/CD44+ cells isolated from early and late stages of organoid development.

cd29 Also found in: Wikipedia . a type I transmembrane protein present on some CD4 helper T cells, platelets, and dendritic cells that is involved in cell-cell or cell-matrix adhesion.

2024年6月25日 · CD29 agonists work by binding to the CD29 receptor and stimulating its activity. CD29 is a subunit of integrin receptors, which are transmembrane proteins that mediate the attachment between a cell and its surroundings, including the …