CD27 is a member of the tumor necrosis factor receptor superfamily. [5] It is currently of interest to immunologists as a co-stimulatory immune checkpoint molecule, and is the target of an anti …

Dec 24, 2024 · CD27 (CD27 Molecule) is a Protein Coding gene. Diseases associated with CD27 include Lymphoproliferative Syndrome 2 and Combined T Cell And B Cell Immunodeficiency. …

The Traf-linked tumor necrosis factor receptor family member CD27 is known as a T cell costimulatory molecule.

CD27 is a costimulatory molecule associated with CD27 Deficiency, a condition characterized by immunodeficiency, EBV lymphoproliferative disease, reduced T cell proliferation, and …

CD27 is a lymphocyte-specific member of the tumour necrosis factor receptor (TNF-R) family, expression of which is tightly regulated during T-cell ontogeny. Recently, the ligand for CD27 …

The CD27 agonistic antibody varlilumab showed promising efficacy in haematological as well as solid cancers. Current studies investigate the combination of the CD27 agonistic antibody …

The CD27 − memory population was the only cell population that displayed a clear-cut recall response to all four antigens . The CD27 + memory population showed a recall response as …

Feb 13, 2024 · CD27-costimulated chimeric antigen receptor (CAR)-engineered T cells exhibited improved tumor control compared with CD28-costimulated CAR-T cells. Thus, CD27 signaling …

Cluster of differentiation 27 (CD27) is a member of the tumour necrosis factor receptor superfamily and plays a key role in T-cell activation by providing a costimulatory signal. Bound …

May 1, 2000 · Memory B cells generate immunoglobulins rapidly and vigorously in the secondary immune response. Here, Kazunaga Agematsu and colleagues highlight studies confirming that …