CD15 is present on almost all Reed–Sternberg cells, including their rare mononuclear variants, and, as such, can be used in immunohistochemistry to identify the presence of such cells in biopsies. The presence of these cells is diagnostic of Hodgkin's lymphoma.

2008年10月19日 · The glycan determinant CD15 (also known as Lewis x, or Lex) is a distinguishing marker for human myeloid cells and mediates neutrophil adhesion to dendritic cells.

CD15, the X hapten or Lewis X antigen, can be identified with the LeuM1 antibody. Originally noted as a monocyte/myeloid cell marker, it was recognized as a marker for the Reed-Sternberg cells of classical Hodgkin lymphoma.

The glycan determinant CD15 (also known as Lewis x, or Le(x)) is a distinguishing marker for human myeloid cells and mediates neutrophil adhesion to dendritic cells. Despite broad interest in this structure, the mechanisms underlying CD15 expression remain relatively uncharacterized.

CD15 (3-fucosyl-N-acetyl-lactosamine) is a cluster of differentiation antigen – an immunologically significant molecule. CD15 is a carbohydrate adhesion molecule (1) that can be expressed on glycoproteins, glycolipids and proteoglycans.

2022年4月28日 · CD15 (Lewis X/Lex) is a fucosyl (3-fucosly-N-acetyl-lactosamine) moiety found on membrane proteins of various cancer cells. These cancers include renal cancer, prostate and bladder cancers, acute leukaemias, hepatocellular carcinoma, breast cancer and melanoma.

CD15 is a haemopoietic differentiation antigen expressed on most terminally differentiated myeloid cells including granulocytes, eosinophils, mast cells, monocytes/macrophages, and Langerhans’ cells.

CD15 + Cells Represent the Myeloid Progenitor Cells in Bone Marrow. CD15 is expressed on myeloid precursor cells, neutrophils, eosinophils, monocytes, myeloid leukemia, and myeloid cell lines . The following features identify the purified cells as being myeloid progenitor cells.

2022年4月28日 · CD15 may serve as a prognostic marker for patients and there are high hopes for its use in the immunotherapeutic treatment of tumours. CD15s is a sialyl derivative of CD15 that possesses its own unique characteristics.

2025年2月20日 · CD15 is a carbohydrate-based molecule expressed on the surface of certain cells, notably in the immune system. Detailed Explanation of CD15. CD15 serves as a marker that helps identify specific cell types. Here's a more detailed breakdown: Cellular Expression: CD15 is found on: Granulocytes: Specifically, the granulocytic series after the ...