CD2 (cluster of differentiation 2) is a cell adhesion molecule found on the surface of T cells and natural killer (NK) cells. It has also been called T-cell surface antigen T11/Leu-5, LFA-2, [ 5 ] LFA-3 receptor, erythrocyte receptor and rosette receptor.

The glycoprotein CD2 is a costimulatory receptor expressed mainly on T and NK cells that binds to LFA3, a cell surface protein expressed on e.g., antigen-presenting cells.

2023年7月7日 · CD markers, also known as CD antigens, are specific types of molecules found on the surface of cells that help differentiate one cell type from another. In fact, the initials "CD" stands for "cluster of differentiation," the nomenclature of which was first established in 1982.

2020年6月8日 · Overall, CD2 is an attractive target for monoclonal antibodies intended for treatment of pathologies characterized by undesired T cell activation and offers an avenue to more selectively target memory T cells while favoring immune regulation.

The CD2 molecule is a 50-55KD transmembrane glycoprotein expressed on the vast majority of thymocytes and virtually all peripheral T lymphocytes. Its functions are two-fold: adhesion and activation.

2024年11月26日 · Conditioning drill 2 consists of five advanced exercises that require more complex plyometric and bilateral movement skills while challenging the components of strength, endurance, and mobility. Army Conditioning Drill 2 has five exercises:

CD2 is a transmembrane molecule belonging to the immunoglobulin supergene family that plays a crucial role in T-cell activation, cytolysis, apoptosis, and cytokine production. It is expressed by thymic T-cells, peripheral T-cells, NK cells, and a subset of …