The chemokine (C-X-C motif) ligand 1 (CXCL1) is a small peptide belonging to the CXC chemokine family that acts as a chemoattractant for several immune cells, especially neutrophils [5] [6] or other non-hematopoietic cells to the site of injury or infection and plays an important role in regulation of immune and inflammatory responses. It was ...

Dec 24, 2024 · CXCL1 (C-X-C Motif Chemokine Ligand 1) is a Protein Coding gene. Diseases associated with CXCL1 include Tonsillitis and Bacterial Meningitis . Among its related pathways are MIF Mediated Glucocorticoid Regulation and GPCR downstream signalling .

Jan 12, 2022 · CXCL1 is one of the most important chemokines, part of a group of chemotactic cytokines involved in the development of many inflammatory diseases. It activates CXCR2 and, at high levels, CXCR1.

This review describes the role of CXCL1, a chemokine crucial in inflammation as a chemoattractant for neutrophils, in physiology and in selected major non-cancer diseases. Due to the vast amount of available information, we focus on the role CXCL1 ...

CXCL1, known as growth related oncogene, can be expressed in many immune cells and neurons. The main function of CXCL1 is recruitment of immunocytes, especially neutrophils [ 8 ]. It can promote proinflammatory reaction, immune regulation and angiogenesis.

Aug 29, 2018 · Here in, cytokine array validated that C-X-C motif chemokine ligand 1 (CXCL1) is the most abundant chemokine secreted by TAMs, and CXCL1 can promote breast cancer migration and invasion...

Mar 8, 2025 · Title: CXCL1 promoted the migration and invasion abilities of oral cancer cells and might serve as a promising marker of prognosis in tongue cancer. Submit: New GeneRIF Correction See all GeneRIFs (231)