CDKN2A, also known as cyclin-dependent kinase inhibitor 2A, is a gene which in humans is located at chromosome 9, band p21.3. [5] It is ubiquitously expressed in many tissues and cell …

2023年7月17日 · What is my cancer risk if I have a CDKN2A mutation? If you have a mutation in the CDKN2A gene, this means you have a condition called Familial Atypical Multiple Mole …

2024年12月24日 · CDKN2A (Cyclin Dependent Kinase Inhibitor 2A) is a Protein Coding gene. Diseases associated with CDKN2A include Melanoma, Cutaneous Malignant 2 and Melanoma …

The CDKN2A gene provides instructions for making several proteins. The most well-studied are the p16 (INK4A) and the p14 (ARF) proteins. Both function as tumor suppressors, which …

1997年1月1日 · CDKN2A, the gene encoding the cell-cycle inhibitor p16CDKN2A, was first identified in 1994. Since then, somatic mutations have been observed in many cancers and …

2024年9月6日 · An inherited CDKN2A mutation may affect your options for cancer prevention, detection and treatment. Learn more here. FORCE is here to guide you.

CDKN2A was a cuproptosis-related gene in regulating chemotherapy resistance by the MAGE-A family in breast cancer: based on artificial intelligence (AI)-constructed pan-cancer risk model.

CDKN2A (cyclin dependent kinase inhibitor 2A, OMIM 600160) is a tumor suppressor gene that encodes for two proteins, namely p16 INK4A and p14 ARF, critical for the regulation of cell …

The CDKN2A gene encodes proteins that regulate 2 critical cell cycle regulatory pathways, the p53 (TP53; 191170) pathway and the RB1 pathway. Through the use of shared coding regions …

4 天之前 · 3.1 Status CDKN2A, CDK4 and known melanoma risk genes. Most of the index individuals included in the study were previously tested and found negative for germline …