
CD79A - Wikipedia
Cluster of differentiation CD79A also known as B-cell antigen receptor complex-associated protein alpha chain and MB-1 membrane glycoprotein, is a protein that in humans is encoded by the CD79A gene. [5]
CD79A Gene - GeneCards | CD79A Protein | CD79A Antibody
2024年12月24日 · CD79A (CD79a Molecule) is a Protein Coding gene. Diseases associated with CD79A include Agammaglobulinemia 3, Autosomal Recessive and Agammaglobulinemia 3. Among its related pathways are Autodegradation of the E3 …
CD79 - Wikipedia
CD79 is composed of two distinct chains called CD79A and CD79B (also known as Igα and Igβ); these form a heterodimer on the surface of a B cell stabilized by disulfide bonding. [1] CD79a and CD79b are both members of the immunoglobulin superfamily.
CD79a: a novel marker for B-cell neoplasms in routinely processed ...
1995年8月15日 · In this report, we describe a new anti-CD79a monoclonal antibody, JCB117, which reacts with human B cells in paraffin embedded tissue sections, including decalcified bone marrow trephines.
B-Cell Receptor Signaling and Beyond: The Role of Igα (CD79a…
Igα (CD79a)/Igβ (CD79b) are essential components of BCR that are indispensable for its functionality, signal initiation, and signal transduction. CD79a/CD79b-mediated BCR signaling is required for the survival of normal as well as malignant B cells via a wide signaling network.
Mechanism of CD79A and CD79B Support for IgM+ B Cell Fitness …
2022年11月15日 · Our study highlights that CD79A and CD79B are required for surface IgM expression in human B cells and illuminates the importance of the IgM expression level for signaling and fitness.
Clinicopathological significance of CD79a expression in classic …
As the clinical significance of B-cell markers has yet to be fully elucidated, this study aimed to clarify the clinicopathological significance of CD79a in 55 patients with CHL. They were immunohistochemically divided into two groups, comprising of 20 CD79a-positive and 35 CD79a-negative patients.
B-Cell Receptor Signaling and Beyond: The Role of Igα (CD79a…
2023年12月19日 · Igα (CD79a)/Igβ (CD79b) are essential components of BCR that are indispensable for its functionality, signal initiation, and signal transduction. CD79a/CD79b-mediated BCR signaling is required for the survival of normal as well as malignant B cells via a wide signaling network.
CD79A CD79a molecule [Homo sapiens (human)] - Gene - NCBI
2025年1月4日 · Title: Mechanism of CD79A and CD79B Support for IgM+ B Cell Fitness through B Cell Receptor Surface Expression. CD79a promotes CNS-infiltration and leukemia engraftment in pediatric B-cell precursor acute lymphoblastic leukemia.
CD79A CD79a molecule - NIH Genetic Testing Registry (GTR)
2024年3月5日 · Selective IgA Deficiency May Be an Underrecognized Risk Factor for Severe COVID-19. CD79a promotes CNS-infiltration and leukemia engraftment in pediatric B-cell precursor acute lymphoblastic leukemia.