The importance of CD45RB expression on T cells was already shown in mice where CD45RB(high) expression determines pathogenic potential. In this study, we analyzed the …

2024年3月1日 · cd45的抗体包括名称分别为cd45、cd45ra、cd45rb、cd45ro、cd45r的不同抗体。 Mouse CD45蛋白有两个等位的基因，CD45.1和CD45.2，其中CD45.1的小鼠品系包括FVB …

2020年2月4日 · Krummey et al. show that viral CD8+ T cell memory has heterogeneous CD45 isoform expression. Low-affinity CD8+ T cells have high CD45RB expression and a …

We investigate two subsets of CD45RA-CD45RO+ CD4+ human T cells which differ by fourfold in their expression of the CD45RB isoform; one is CD45RBbright and the other is …

2024年8月9日 · Our results thus identify that stably expressed CD45RB levels can be exploited to trace resting memory B cells and their activated progeny, and suggest that atypical and non …

CD45RB is a receptor-type protein tyrosine phosphatase, CD45 glycoprotein. CD45 is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family …

CD45RBhi and CD45RBlo memory cells that underwent homeo-static proliferation in a sub-lethally irradiated host largely main-tain pre-transfer CD45RB expression levels (82% for …

CD45RB contains only one of the three alternatively spliced exons (exon 5). CD45RB is an isoform of CD45 with exon 5 splicing (encodes B determinant). It is a 220 kD glycoprotein …

数据显示 CD45 的交联，特别是 CD45RB 同种型，增强小胶质细胞对 Abeta(1-42) 肽的吞噬作用，并抑制 LPS 诱导的 p44/42 和 p38 通路激活。 小胶质细胞与激动剂 CD45 抗体的共同处理 …

2001年5月1日 · CD45 (also known as B220, CD45R, CD45RA, CD45RB, CD45RC, CD45RO, EC 3.1.3.48, LCA, T200, Ly5 and PTPRC) was cloned as a major leukocyte cell surface molecule …