
CD303 (BDCA-2) - a potential novel target for therapy in
CD303 is another specific surface marker of human pDCs, centrally involved in antigen presentation and immune tolerance. Monoclonal antibodies directed against CD303 have been …
BDCA-2 (CD303): a highly specific marker for normal and …
2013年7月11日 · Montes-Moreno et al recently reported the usefulness of SPIB as a novel immunohistochemical marker for supporting the diagnosis of blastic plasmacytoid dendritic cell …
CD303 (BDCA-2) Antibody, anti-human | Miltenyi Biotec | USA
The CD303 (BDCA-2) antigen is a novel type II transmembrane C-type lectin. 3 Remarkably, plasmacytoid dendritic cells can take up ligands via CD303 (BDCA-2), then process and …
CLEC4C - Wikipedia
CLEC4C is a membrane protein of plasmacytoid dendritic cells used as a marker for this kind of cells and denoted as CD303 in the nomenclature of the Cluster of differentiation. [1]
CD303 - Overview: CD303 (BDCA-2) Immunostain, Technical …
CD303 (BDCA-2) is a highly specific marker for normal and neoplastic plasmacytoid dendritic cells and may be useful as a specific marker for the diagnosis of blastic plasmacytoid dendritic cell …
Improved in vitro and in vivo activity against CD303-expressing …
In this study, a glyco-engineered anti-CD303 antibody (ch122A2 mAb) has been generated and further characterized. In vitro and in vivo studies demonstrate its ability to efficiently deplete …
CD303 (BDCA‐2) signals in plasmacytoid dendritic cells via a …
CD303 (BDCA-2) is a type II c-type lectin specifically expressed by human PDC. CD303 signaling induces tyrosine phosphorylation and Src kinase dependent calcium influx. Cross-linking …
CD303 (BDCA-2) signals in plasmacytoid dendritic cells via a ... - PubMed
CD303 (BDCA-2) is a type II c-type lectin specifically expressed by human PDC. CD303 signaling induces tyrosine phosphorylation and Src kinase dependent calcium influx. Cross-linking …
Improved in vitro and in vivo activity against CD303 ... - PubMed
We are proposing here, as a new targeted-based therapy, a novel chimeric monoclonal antibody (mAb) that mediates a strong cellular cytotoxicity directed against a specific human pDC …
CD303 (BDCA-2) Immunostain, Technical Component Only
CD303 (BDCA-2) is a highly specific marker for normal and neoplastic plasmacytoid dendritic cells and may be useful as a specific marker for the diagnosis of blastic plasmacytoid dendritic cell …