CD303 is another specific surface marker of human pDCs, centrally involved in antigen presentation and immune tolerance. Monoclonal antibodies directed against CD303 have been …

2013年7月11日 · Montes-Moreno et al recently reported the usefulness of SPIB as a novel immunohistochemical marker for supporting the diagnosis of blastic plasmacytoid dendritic cell …

The CD303 (BDCA-2) antigen is a novel type II transmembrane C-type lectin. 3 Remarkably, plasmacytoid dendritic cells can take up ligands via CD303 (BDCA-2), then process and …

CLEC4C is a membrane protein of plasmacytoid dendritic cells used as a marker for this kind of cells and denoted as CD303 in the nomenclature of the Cluster of differentiation. [1]

CD303 (BDCA-2) is a highly specific marker for normal and neoplastic plasmacytoid dendritic cells and may be useful as a specific marker for the diagnosis of blastic plasmacytoid dendritic cell …

In this study, a glyco-engineered anti-CD303 antibody (ch122A2 mAb) has been generated and further characterized. In vitro and in vivo studies demonstrate its ability to efficiently deplete …

CD303 (BDCA-2) is a type II c-type lectin specifically expressed by human PDC. CD303 signaling induces tyrosine phosphorylation and Src kinase dependent calcium influx. Cross-linking …

CD303 (BDCA-2) is a type II c-type lectin specifically expressed by human PDC. CD303 signaling induces tyrosine phosphorylation and Src kinase dependent calcium influx. Cross-linking …

We are proposing here, as a new targeted-based therapy, a novel chimeric monoclonal antibody (mAb) that mediates a strong cellular cytotoxicity directed against a specific human pDC …

CD303 (BDCA-2) is a highly specific marker for normal and neoplastic plasmacytoid dendritic cells and may be useful as a specific marker for the diagnosis of blastic plasmacytoid dendritic cell …