CD30, also known as TNFRSF8 (TNF receptor superfamily member 8), [5] is a cell membrane protein of the tumor necrosis factor receptor family and a tumor marker. This receptor is expressed by activated, but not by resting, T and B cells.

CD30, also known as BerH2, Ki1 or TNFRSF8, is a transmembrane glycoprotein receptor that belongs to the tumor necrosis factor receptor (TNFR) and was first identified in Hodgkin lymphoma cell lines but also expressed in normal activated B and T cells.

What are primary cutaneous CD30+ lymphoproliferative disorders? Primary cutaneous CD30+ lymphoproliferative disorders (LPD) are indolent-behaving extranodal T-cell neoplasms localised to the skin and characterised by CD30 expression on atypical lymphocytes.

CD30 is a protein made primarily by activated immune cells such as T cells and B cells. Some types of cancers that start from T cells or B cells, such as anaplastic large cell lymphom a and Hodgkin lymphoma also express CD30.

2024年12月18日 · Primary cutaneous CD30 positive T cell lymphoproliferative disorder describes a group of immune system cancers involving T cells that express a protein called CD30. These cancers primarily affect the skin and are part of a spectrum of related conditions.

CD30 is a member of the tumor necrosis factor receptor superfamily. It is characteristically expressed in certain hematopoietic malignancies, including anaplastic large cell lymphoma...

2000年12月1日 · The anaplastic large B-cell lymphoma might be derived from CD30 + germinal center B cells (as are most diffuse large B-cell lymphomas) because they carry—like reactive germinal center B cells and the nonanaplastic CD30 − diffuse large B-cell lymphoma—somatic mutations in their rearranged variable Ig genes.75 This supports the close ...

2023年7月5日 · CD30, also known as TNFRSF8 (tumor necrosis factor receptor superfamily member 8), is a protein receptor that is heavily glycosylated inside the Golgi apparatus, as well as a tumor marker that is found on the surface of specific cells in the body, including certain immune cells and cancer ones.

The transmembrane receptor CD30 (TNFRSF8) and its ligand CD30L (CD153, TNFSF8) are members of the tumor necrosis factor (TNF) superfamily and display restricted expression in subpopulations of activated T-and B-cells in nonpathologic conditions. CD30 expression is...

The CD30 protein is a type of tumor necrosis factor receptor and a type of tumor marker. A protein found on some T cells and B cells (two types of white blood cells). It is a receptor for a protein called tumor necrosis factor, which is involved in cell growth and cell survival.