Proto-oncogene c-KIT is the gene encoding the receptor tyrosine kinase protein known as tyrosine-protein kinase KIT, CD117 (cluster of differentiation 117) or mast/stem cell growth …

Jun 9, 2022 · CD117 is a proto-oncogene activated in GIST tumors, receptor for kit protein, a 145 kD tyrosine kinase growth factor receptor protein

Measuring the amount of CD117 in tumor tissue may help diagnose cancer and plan treatment. CD117 is a type of receptor tyrosine kinase and a type of tumor marker. Also called c-kit and …

CD117 is a transmembrane protein receptor encoded by the c-kit proto-oncogene. The CD117 ligand is stem cell factor, an important hematopoietic regulator. CD117 is present on …

CD117 (KIT) is a type III receptor tyrosine kinase operating in cell signal transduction in several cell types. Normally KIT is activated (phosphorylated) by binding of its ligand, the stem cell factor.

CD117, also known as c-kit, is a tyrosine kinase receptor that is expressed in most hemopoietic stem and progenitor cells, as well as mast cells. It is a marker used for the detection of mast …

CD117, also known as c-kit, is a protein that acts as a receptor on the surface of specific cells in the body. It is involved in cell growth, survival, and development, particularly in cells that form …