
Pathology Outlines - Stains & CD markers
2025年3月4日 · Immunostains, routine stains and CD markers at PathologyOutlines.com. Page views in 2025 to date (this page and chapter topics): 734,940
Pathology Outlines - CD30
Diffuse large B cell lymphoma; CD30 expressed in 10 - 15% of cases (Hum Pathol 2017;60:160, Mod Pathol 2015;28:1202) Follicular lymphoma (Arch Pathol Lab Med 2022 Apr 26 [Epub ahead of print]) Lymphomatoid granulomatosis (Am J Surg Pathol 2015;39:141) Plasmablastic lymphoma; expressed in 20 - 30% of cases (Blood 2015;125:2323)
Pathology Outlines - Classic Hodgkin lymphoma
2025年3月7日 · Bimodal age distribution: peaks at 15 - 35 years and 50 - 70 years Epidemiology varies by subgroup (Br J Haematol 2019;184:45): Nodular sclerosis (~70% of CHL in Western countries): F > M, age 15 - 35 years, most common in urban areas, wealthier nations and individuals with high socioeconomic status, minority (10 - 25%) EBV+
Pathology Outlines - CD56
2023年2月9日 · Primary cutaneous gamma delta T cell lymphoma (Cureus 2023;15:e35442) Other Alveolar rhabdomyosarcoma (Hum Pathol 2009;40:341, Mod Pathol 2008;21:795) Cardiac ischemic damage (Verh Dtsch Ges Pathol 2004;88:246) Extrahepatic biliary atresia (Am J Surg Pathol 2003;27:1454)
Gross cystic disease fluid protein 15 (GCDFP-15)
2024年4月17日 · It can be used in differentiating primary and secondary extramammary Paget disease. GCDFP-15 is positive in primary extramammary Paget disease while negative in secondary extramammary Paget disease (Arch Pathol Lab Med 1998;122:1077). Answer B is incorrect because GCDFP-15 does not show independent prognostic power over hormone …
Pathology Outlines - CD5
2025年1月30日 · Some studies report lower or varied CD5 positivity rates in atypical forms (Cancers [Basel] 20223;15:4427) B cell chronic lymphocytic leukemia (80 - 93%) (Leuk Lymphoma 1998;31:209) T cell acute lymphoblastic leukemia (T ALL) Mantle cell lymphoma (95%) (Am J Surg Pathol 2019;43:1052)
Pathology Outlines - CD138
2024年6月13日 · Involved in cell proliferation, migration, adhesion and angiogenesis with loss of CD138 expression leading to enhanced motility and invasion of neoplastic cells (Oncotarget 2015;6:28693)
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2023年1月17日 · Liver (bile canaliculi, biliary epithelium), mesonephric remnants, myoepithelial cells (breast) (Am J Surg Pathol 2003;27:178, Mod Pathol 2002;15:397, J Clin Pathol 2004;57:625) Ovary, placenta (cytotrophoblast, intermediate trophoblast, syncytiotrophoblast), prostate basal and secretory cells
Pathology Outlines - CD20
2021年9月20日 · 90% of B cell lymphomas, although B cell lymphomas are CD20 negative after rituximab and other B cell markers (CD19, CD79a, PAX5) should be used (Am J Clin Pathol 2006;126:534, Biomark Res 2017;5:5, Ann Hematol 2020;99:2141)
Pathology Outlines - CD123
CD123 / interleukin 3 receptor alpha chain (IL3Rα) is upregulated and overexpressed in a variety of myeloid and lymphoid neoplasms