Bone morphogenetic proteins are known for their ability to induce bone and cartilage development. BMP10 is categorized as a BMP since it shares a large sequence homology with other BMP's in the TGF-β superfamily.

2023年3月16日 · We aimed to assess the predictive value of the novel atrial‐specific biomarker BMP10 (bone morphogenetic protein 10) for death and MACE in patients with AF in comparison with NT‐proBNP (N‐terminal prohormone of B‐type natriuretic peptide).

2024年12月24日 · BMP10 (Bone Morphogenetic Protein 10) is a Protein Coding gene. Diseases associated with BMP10 include Myostatin-Related Muscle Hypertrophy and Pulmonary Hemosiderosis. Among its related pathways are Apoptotic Pathways in Synovial Fibroblasts and MIF Mediated Glucocorticoid Regulation.

BMP10 is the only biomarker associated with high pulmonary vascular resistance (PVR) independent of left atrial filling pressure. Because pulmonary arterial pressure depends on both PVR (pre-capillary component of mPAP) and left atrial filling pressure (post-capillary component of mPAP, measured by PAWP), we determined the association of biomarkers with these …

2025年1月4日 · BMP10, is elevated in the stenotic colon segment of Hirschsprung disease patients, and BMP10 signaling may play a pivotal role in disease development. Low expression of bone morphogenetic protein-10 is associated with urothelial cancer of the bladder.

Here we describe an essential role of BMP10 in regulating cardiac growth and chamber maturation. BMP10 null mice display ectopic and elevated expression of p57 (kip2) and a dramatic reduction in proliferative activity in cardiomyocytes at E9.0-E9.5.

2024年5月17日 · BMP10 is a newly identified cardiac-specific protein. In recent years, reports have emphasized the effects of BMP10 on myocardial apoptosis, fibrosis and immune response, as well as its synergistic effects with BMP9 in vascular endothelium and role in …

2020年12月18日 · BMP9 and BMP10 (bone morphogenetic protein) are known to regulate endothelial quiescence after secretion from the liver and right atrium, whereas a direct role in the regulation of VSMCs was not investigated. We studied the role of BMP9 and BMP10 for controlling formation of contractile VSMCs.

2019年12月27日 · Bone morphogenetic protein 10 (BMP10) is a cardiac peptide growth factor belonging to the transforming growth factor β superfamily that critically controls cardiovascular development, growth, and maturation.

BMP10 is a newly identified cardiac-specific protein. In recent years, reports have emphasized the effects of BMP10 on myocardial apoptosis, fibrosis and immune response, as well as its synergistic effects with BMP9 in vascular endothelium and role in endothelial dysfunction.