ATOX1 - Wikipedia
ATOX1 is a copper metallochaperone protein that is encoded by the ATOX1 gene in humans. [5] [6] In mammals, ATOX1 plays a key role in copper homeostasis as it delivers copper from the …
ATOX1 Gene - GeneCards | ATOX1 Protein | ATOX1 Antibody
Dec 24, 2024 · ATOX1 (Antioxidant 1 Copper Chaperone) is a Protein Coding gene. Diseases associated with ATOX1 include Menkes Disease and Wilson Disease. Among its related …
SCI | 铜稳态和铜死亡相关最新研究进展 - 知乎 - 知乎专栏
Dec 19, 2022 · 伴侣抗氧化剂1 (atox1)负责将铜转移到高尔基体反面网络 (tgn) 中的atp7a和atp7b，并促进赖氨酰氧化酶、酪氨酸酶和血浆铜蓝蛋白等铜酶的合成（图 1）。 伴侣蛋 …
Nat Rev | 癌症中的铜增生和铜死亡 - 知乎 - 知乎专栏
Mar 30, 2024 · 铜离子可以通过抗氧化剂1铜伴侣（atox1）携带到反式高尔基网络。atox1与细胞质中的cu（i）结合，并将其递送至高尔基体网络中的铜转运atp酶，如atp7a和atp7b（图1） …
The Role of Copper Chaperone Atox1 in Coupling Redox …
Human antioxidant protein 1 (Atox1) is a small cytosolic protein with an essential role in copper homeostasis. Atox1 functions as a copper carrier facilitating copper transfer to the secretory …
Targeting cuproplasia and cuproptosis in cancer - Nature
Mar 14, 2024 · Copper is also transported to the trans-Golgi by antioxidant 1 copper chaperone (ATOX1). Copper can be delivered by CCS to the nucleus, where it activates transcription …
The ATOX1 Gene Role in Copper Metabolism and the …
Sep 13, 2023 · The ATOX1 (Antioxidant Protein 1) is a human copper metal chaperone that plays an important role in cellular copper homeostasis. The protein is responsible for cytosolic …
Novel Role of Antioxidant-1 (Atox1) as a Copper-dependent …
The present study with re-expression of nuclear-targeted Atox1 in Atox1-/-cells strongly suggests that it is nuclear Atox1 that plays an essential role in copper-stimulated increases in cyclin D1 …
抗氧化因子 1 铜伴侣（ATOX1）基因 | MCE - MCE-生物活性 ...
抗氧化因子 1 铜伴侣： 该基因编码一个铜伴侣蛋白，它通过将胞质铜结合并转运到反式高尔基体网络中的 ATP 酶蛋白，以便随后掺入血浆铜蓝蛋白，从而在铜稳态中发挥作用。这种蛋白质还 …
文献解读：Memo1与铜伴侣结合蛋白-Atox1相互作用，结合还原 …
铜伴侣蛋白 Atox1，能够将细胞质中的Cu（I）从铜输入器Ctr1移动到高尔基网络中的 ATP 酶 ATP7A 和 ATP7B，以负载分泌通路中的Cu依赖酶，促进癌细胞的迁移。