2024年12月24日 · ATOX1 (Antioxidant 1 Copper Chaperone) is a Protein Coding gene. Diseases associated with ATOX1 include Menkes Disease and Wilson Disease. Among its related …

Human antioxidant protein 1 (Atox1) is a small cytosolic protein with an essential role in copper homeostasis. Atox1 functions as a copper carrier facilitating copper transfer to the secretory …

The present study with re-expression of nuclear-targeted Atox1 in Atox1-/-cells strongly suggests that it is nuclear Atox1 that plays an essential role in copper-stimulated increases in cyclin D1 …

2025年2月8日 · copper transport protein ATOX1, ATX1 antioxidant protein 1 homolog, metal transport protein ATX1. GeneRIFs: Gene References Into Functions. Atox1-cyclin D1 loop …

ATOX1 is responsible for delivering copper to copper-dependent enzymes involved in antioxidant defense and extracellular matrix remodeling. ATOX1-mediated dysregulation of copper …

2024年3月14日 · Copper is also transported to the trans-Golgi by antioxidant 1 copper chaperone (ATOX1). Copper can be delivered by CCS to the nucleus, where it activates transcription …

2024年12月10日 · Title: Memo1 binds reduced copper ions, interacts with copper chaperone Atox1, and protects against copper-mediated redox activity in vitro. Copper enhances …

2008年4月4日 · Here we show that antioxidant-1 (Atox1), previously appreciated as a copper chaperone, represents a novel copper-dependent transcription factor that mediates copper …

2023年9月13日 · This review collects data on the antioxidant role of ATOX1, the gene role’s in the angiogenesis regulation and cancer cell proliferation, and its role in the pathogenesis of …

2017年11月11日 · We show that the copper chaperone Atox1, which delivers copper to ATP7B, and the group of the first three metal-binding domains (MBD1–3) are central to the activity …