
Adipose Triglyceride Lipase Regulation: An Overview - PubMed
Adipose triglyceride lipase (ATGL) is the key-enzyme for the release of fatty acids (FAs) from triacylglycerol (TG) stores during intracellular lipolysis producing FAs used for energy production.
Adipose Triglyceride Lipase Regulation: An Overview - PMC
Adipose triglyceride lipase (ATGL) is the key-enzyme for the release of fatty acids (FAs) from triacylglycerol (TG) stores during intracellular lipolysis and produces FAs used for energy production.
Of mice and men: The physiological role of adipose triglyceride …
Adipose triglyceride lipase (ATGL) has been discovered 14 years ago and revised our view on intracellular triglyceride (TG) mobilization – a process termed lipolysis. ATGL initiates the hydrolysis of TGs to release fatty acids (FAs) that are crucial ...
ATGL is a biosynthetic enzyme for fatty acid esters of hydroxy …
2022年6月8日 · Here we identified adipose triglyceride lipase (ATGL, also known as patatin-like phospholipase domain containing 2 (PNPLA2)) as a candidate biosynthetic enzyme for FAHFAs using chemical biology...
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ATGL is a biosynthetic enzyme for fatty acid esters of hydroxy …
Here we identified adipose triglyceride lipase (ATGL, also known as patatin-like phospholipase domain containing 2 (PNPLA2)) as a candidate biosynthetic enzyme for FAHFAs using chemical biology and proteomics.
Mutational scanning pinpoints distinct binding sites of key ATGL ...
2024年3月21日 · ATGL is a key enzyme in intracellular lipolysis and plays an important role in metabolic and cardiovascular diseases. ATGL is tightly regulated by a known set of protein-protein interaction...
ATGL: Key Insights Into Lipid Metabolism and Regulation
5 天之前 · ATGL-generated free fatty acids serve as precursors for the synthesis of bioactive lipids, impacting cellular signaling and inflammation. In the liver, ATGL activity affects the balance between lipogenesis and lipolysis, influencing hepatic lipid content and contributing to conditions like non-alcoholic fatty liver disease (NAFLD) when ...
The role of adipose triglyceride lipase in lipid and glucose ...
2019年11月22日 · ATGL catalyses the initial step in adipose triglyceride lipolysis, working in concert with other enzymes to mobilize triglyceride for energy production. In addition to the role of ATGL in adipose tissue triglyceride mobilization, ATGL plays crucial roles in regulating lipid homeostasis in other tissues.
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