Autophagy-related protein 13 - Wikipedia
Autophagy-related protein 13 also known as ATG13 is a protein that in humans is encoded by the KIAA0652 gene. [5] ATG13 is an autophagy factor required for phagosome formation. ATG13 …
ATG13 Gene - GeneCards | ATG13 Protein | ATG13 Antibody
Dec 24, 2024 · ATG13 (Autophagy Related 13) is a Protein Coding gene. Diseases associated with ATG13 include Prostate Cancer and Liver Carcinoma In Situ. Among its related pathways …
自噬相关 13（ATG13）基因 | MCE - MCE-生物活性分子大师
Ubiquitous expression in testis (RPKM 17.3), brain (RPKM 12.2) and 25 other tissues. 该基因编码的蛋白质是自噬因子和 TOR 激酶信号通路的靶标。 编码的蛋白质对于自噬体形成和线粒体自 …
9776 - Gene ResultATG13 autophagy related 13 [ (human)]
Elevated ATG13 in serum of patients with ME/CFS stimulates oxidative stress response in microglial cells via activation of receptor for advanced glycation end products (RAGE). Circ …
ATG13: just a companion, or an executor of the autophagic …
In vertebrates, the orthologous ULK1 kinase complex contains the Ser/Thr kinase ULK1 and the accessory proteins ATG13, RB1CC1, and ATG101. Among these components, Atg1/ULK1 …
The molecular mechanism of Atg13 function in autophagy ... - PubMed
Mar 4, 2017 · Atg13 is an essential subunit of the Atg1 autophagy initiation complex in yeast and its mammalian counterpart, ATG13, is indispensable for autophagy induction by the ULK1 …
The ATG1/ATG13 protein kinase complex is both a regulator and …
The process is induced by various nutrient-responsive signaling cascades converging on the Autophagy-Related1 (ATG1)/ATG13 kinase complex. Here, we describe the ATG1/13 …
The molecular mechanism of Atg13 function in autophagy …
Atg13 is an essential subunit of the Atg1 autophagy initiation complex in yeast and its mammalian counterpart, ATG13, is indispensable for autophagy induction by the ULK1 complex.
Atg13在自噬诱导中发挥作用的分子机制：数据背后隐藏着什 …
Jan 25, 2017 · Atg13是酵母中Atg1自噬起始复合物的必需亚基，其哺乳动物对应物ATG13对于ULK1复合物的自噬诱导是必不可少的。 蛋白质的N端折叠成一个HORMA结构域，该结构已 …
合肥研究院揭示ULK1/ATG13调控有丝分裂期自噬及肿瘤生长的重 …
Jun 15, 2020 · 自噬是真核生物中发现的保守降解机制，主要有自噬相关蛋白（atg）执行自噬过程，ulk1/atg13是最上游的自噬起始复合物。 细胞周期由间期和分裂期组成；一般而言，非同步 …
The Intrinsically Disordered Protein Atg13 Mediates …
Atg13, via an intrinsically disordered region, provides a flexible linkage between two Atg17 molecules to mediate multimeric Atg1 complex self-assembly for PAS organization.
Atg13 Is Essential for Autophagy and Cardiac Development in Mice
Atg13 -deficient embryos show growth retardation and myocardial growth defects. In cultured fibroblasts, Atg13 deficiency blocks autophagosome formation at an upstream step.
The Atg1-Atg13 Complex Regulates Atg9 and Atg23 Retrieval …
The Atg1-Atg13 complex, localizing to the PAS independently of the PtdIns 3-kinase complex I , initiates retrieval of Atg9 by inducing its interaction with Atg18 and Atg2. The association of …
ULK1-ATG13 and their mitotic phospho-regulation by CDK1 …
Jun 9, 2020 · Unc-51-like autophagy activating kinase 1 (ULK1)–autophagy-related 13 (ATG13) is the most upstream autophagy initiation complex that is phosphorylated by mammalian target …
Site-specific Atg13 methylation-mediated autophagy regulates …
Sep 5, 2023 · Atg13-mediated ULK complex initiated autophagy and promoted formation of autophagosome that activated the NF-κB/ NLRP3 signaling pathway in BEAS-2B cells. The …
Atg13 Is Essential for Autophagy and Cardiac Development in Mice
Dec 7, 2015 · Atg13-deficient embryos show growth retardation and myocardial growth defects. In cultured fibroblasts, Atg13 deficiency blocks autophagosome formation at an upstream step. In …
Systematic analysis of ATG13 domain requirements for autophagy ...
Macroautophagy/autophagy is an evolutionarily conserved cellular process whose induction is regulated by the ULK1 protein kinase complex. The subunit ATG13 functions as an adaptor …
Full article: The molecular mechanism of Atg13 function in …
Feb 10, 2017 · Atg13 is an essential subunit of the Atg1 autophagy initiation complex in yeast and its mammalian counterpart, ATG13, is indispensable for autophagy induction by the ULK1 …
Full article: Systematic analysis of ATG13 domain requirements for ...
Macroautophagy/autophagy is an evolutionarily conserved cellular process whose induction is regulated by the ULK1 protein kinase complex. The subunit ATG13 functions as an adaptor …
ATG13 Recombinant Rabbit Monoclonal Antibody (24GB6785)
Western blot analysis of ATG13. Total cell lysates (30 μg) from C2C12, H9c2, HAP-1, HeLa, HepG2, and HT-1080 cell lines were loaded and separated by SDS-PAGE. The blot was …