2024年12月24日 · ARNT (Aryl Hydrocarbon Receptor Nuclear Translocator) is a Protein Coding gene. Diseases associated with ARNT include Renal Cell Carcinoma and Endometriosis. Among its related pathways are Oxidation by cytochrome P450 and Gene expression (Transcription).

The ARNT gene encodes the aryl hydrocarbon receptor nuclear translocator protein that forms a complex with ligand-bound aryl hydrocarbon receptor (AhR), and is required for receptor function.

Incorrect spelling, explanation: in quick speech, when we say aren’t – the short form of are not – we usually omit the letter -e. That, however, happens only in pronunciation, but some users do the same while spelling the form aren’t, which gives arn’t. It is incorrect so make sure you spell it right. Incorrect spelling. Still not sure?

2014年5月13日 · The aryl hydrocarbon receptor nuclear translocator (ARNT), also designated as hypoxia-inducible factor (HIF)-1β, is a transcription factor belonging to the basic helix-loop-helix (bHLH)-Per-ARNT-Sim (PAS) family.

2025年2月9日 · ARNT may modulate reactive oxygen species signaling and drug response in acute myeloid leukemia. ARNT was found to be responsible for establishing the drug-resistant properties of cancer cells by upregulation of MDR1.

ARNT promotes adult hematopoietic stem cell viability through regulation of BCL-2 and VEGF-A expression. Fetal liver hematopoietic progenitors experience hypoxia and loss of hypoxia-induced transcription decreases their survival.

These ARNT-deficient (ARNT −) cells lack ARNT/HIF-1β protein expression and function and provide an opportunity to determine the importance of ARNT/HIF-1β in other aspects of gene regulation. Here we describe the effects of this phenotype on hypoxic gene regulation.