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PubMed
https://pubmed.ncbi.nlm.nih.gov
ALKBH9C, a potential RNA m6 A demethylase, regulates the
In this study, we determined the function of ALKBH9C (At4g36090) in seed germination and seedling growth of Arabidopsis thaliana in response to abiotic stress and abscisic acid (ABA). Seed germination of the alkbh9c mutant was delayed in response to salt, drought, cold and ABA.
Novel AlkB Dioxygenases—Alternative Models for
ALKBH proteins, the homologs of Escherichia coli AlkB dioxygenase, constitute a direct, single-protein repair system, protecting cellular DNA and RN…
nih.gov
ALKBH family members as novel biomarkers and prognostic factors in ...
The ALKBH gene family encodes nine homologous enzymes (ALKBH1-8 and FTO) to repair DNA or RNA depending on Fe2+ and α-ketoglutarate (α-KG), whic…
PubMed
What is alkbh protein used for?
EMBO J. 25, 2189–2198 (2006). Piwowarski, J. et al. Proteins from ALKBH group to be applied in the method of diagnosing tumour diseases, their application for identification of substances with antitumour properties, and derivatives of anthraquinone to be used as the anticancer drug in the tumour disease treatment and/or preventing method.
nature.com
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Hydroboration-oxidation of alkynes | Alkenes and Alkynes | Organic chemistry | Khan Academy
YouTubeKhan Academy Organic Chemistry132.4K viewsAug 2, 2012

nih.gov
https://pmc.ncbi.nlm.nih.gov › articles
Novel AlkB Dioxygenases—Alternative Models for
ALKBH proteins, the homologs of Escherichia coli AlkB dioxygenase, constitute a direct, single-protein repair system, protecting cellular DNA and RNA against the cytotoxic and mutagenic …
PubMed
https://pubmed.ncbi.nlm.nih.gov
ALKBH family members as novel biomarkers and prognostic …
Aug 17, 2022 · The ALKBH gene family encodes nine homologous enzymes (ALKBH1-8 and FTO) to repair DNA or RNA depending on Fe2+ and α-ketoglutarate (α-KG), which is related …
Nature
https://www.nature.com › articles
ALKBH7-mediated demethylation regulates …
Jul 12, 2021 · Members of the mammalian AlkB family are known to mediate nucleic acid demethylation 1, 2. ALKBH7, a mammalian AlkB homologue, …
Author: Li-Sheng Zhang, Li-Sheng Zhang, Qing-Ping Xiong, Sonia Peña Perez, Sonia Peña Perez, Chang Liu, Chan...
Publish Year: 2021
Nature
https://www.nature.com › articles
ALKBH overexpression in head and neck cancer: …
Sep 13, 2019 · Here we discovered the combined overexpression of members of the ALKBH family in head and neck squamous cell carcinomas (HNSCC). We …
Author: Tomaš Pilžys, Michał Marcinkowski, Wojciech Kukwa, Damian Garbicz, Małgorzata Dylewska, Karolina Fer...
Publish Year: 2019
Springer
https://link.springer.com › article
ALKBH1: emerging biomarker and therapeutic target for cancer
Dec 20, 2024 · ALKBH1, possessing demethylase activity, plays indispensable roles in counteracting DNA methylation and facilitating DNA repair, thereby orchestrating methylation …
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What is alkbh group used for?
Piwowarski, J. et al. Proteins from ALKBH group to be applied in the method of diagnosing tumour diseases, their application for identification of substances with antitumour properties, and derivatives of anthraquinone to be used as the anticancer drug in the tumour disease treatment and/or preventing method. Patent application nr PL419848A1.
ALKBH overexpression in head and neck cancer: potential target for
nature.com
What does alkbh7 do?
Zhang et al. identify ALKBH7 as the demethylase of mitochondrial pre-tRNAs that regulates nascent mitochondrial RNA processing and translation. ALKBH7 loss impairs mitochondrial functions including fatty acid oxidation, leading to obesity.
ALKBH7-mediated demethylation regulates mitochondrial ... - Nature
nature.com
What is alkbh protein used for?
EMBO J. 25, 2189–2198 (2006). Piwowarski, J. et al. Proteins from ALKBH group to be applied in the method of diagnosing tumour diseases, their application for identification of substances with antitumour properties, and derivatives of anthraquinone to be used as the anticancer drug in the tumour disease treatment and/or preventing method.
ALKBH overexpression in head and neck cancer: potential target for
nature.com
Can alkbh be used as a marker for cancer diagnosis?
Summing up, overexpression of a single or a group of ALKBH proteins could be used as a marker for cancer diagnosis 18. The samples obtained by biopsy (or surgery) could be subjected to Western blot analysis and adequate chemotherapy, e.g. combination of alkylating agents and antraquinone derivatives, could be established.
ALKBH overexpression in head and neck cancer: potential target for
nature.com
What is the role of alkbhs in normal vs Cancer cells?
The different role of ALKBHs in normal vs cancer cells was also confirmed by the results of subcellular localization using immunofluorescence. In HNSCC we observed the unexpected localization of nuclear proteins ALKBH2 and 5 in the cytoplasm, while ALKBH3 was found only in cytoplasm.
ALKBH overexpression in head and neck cancer: potential target for
nature.com
Are alkbhs a potential target for anticancer therapy?
The relatively high expression of ALKBHs in tumor tissues correlate with cancer development 26, 27 making these proteins the potential targets for anticancer therapy.
ALKBH overexpression in head and neck cancer: potential target for
nature.com
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PubMed
https://pubmed.ncbi.nlm.nih.gov
Multi-substrate selectivity based on key loops and non ... - PubMed
AlkB homologs (ALKBH) are a family of specific demethylases that depend on Fe 2+ and α-ketoglutarate to catalyze demethylation on different substrates, including ssDNA, dsDNA, …
nih.gov
https://pmc.ncbi.nlm.nih.gov › articles
ALKBH family members as novel biomarkers and prognostic …
Abnormal expression of ALKBH members were found in various cancers, and the roles played by it were the focus of attention. The ALKBH gene family encodes nine homologous enzymes …
Springer
https://link.springer.com › article
ALKBH8B, a Putative RNA Demethylase, Plays a Role in the
Apr 19, 2022 · The alpha-ketoglutarate-dependent hydroxylase homolog (ALKBH) proteins, which can remove alkyl and methyl groups from DNAs, have been proposed to function as RNA …
nih.gov
https://pmc.ncbi.nlm.nih.gov › articles
ALKBH overexpression in head and neck cancer: potential target …
Here we discovered the combined overexpression of members of the ALKBH family in head and neck squamous cell carcinomas (HNSCC). We found direct correlation of ALKBH3 and FTO …
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ALKBH9C, a potential RNA m6 A demethylase, regulates the

Novel AlkB Dioxygenases—Alternative Models for

ALKBH family members as novel biomarkers and prognostic …

ALKBH7-mediated demethylation regulates …

ALKBH overexpression in head and neck cancer: …

ALKBH1: emerging biomarker and therapeutic target for cancer

ALKBH overexpression in head and neck cancer: potential target for

ALKBH7-mediated demethylation regulates mitochondrial ... - Nature

ALKBH overexpression in head and neck cancer: potential target for

ALKBH overexpression in head and neck cancer: potential target for

ALKBH overexpression in head and neck cancer: potential target for

ALKBH overexpression in head and neck cancer: potential target for

Multi-substrate selectivity based on key loops and non ... - PubMed

ALKBH family members as novel biomarkers and prognostic …

ALKBH8B, a Putative RNA Demethylase, Plays a Role in the

ALKBH overexpression in head and neck cancer: potential target …

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