In this study, we determined the function of ALKBH9C (At4g36090) in seed germination and seedling growth of Arabidopsis thaliana in response to abiotic stress and abscisic acid (ABA). …

ALKBH proteins, the homologs of Escherichia coli AlkB dioxygenase, constitute a direct, single-protein repair system, protecting cellular DNA and RNA against the cytotoxic and mutagenic …

Aug 17, 2022 · The ALKBH gene family encodes nine homologous enzymes (ALKBH1-8 and FTO) to repair DNA or RNA depending on Fe2+ and α-ketoglutarate (α-KG), which is related …

Jul 12, 2021 · Members of the mammalian AlkB family are known to mediate nucleic acid demethylation 1, 2. ALKBH7, a mammalian AlkB homologue, localizes in mitochondria and …

Sep 13, 2019 · Here we discovered the combined overexpression of members of the ALKBH family in head and neck squamous cell carcinomas (HNSCC). We found direct correlation of …

Dec 20, 2024 · ALKBH1, possessing demethylase activity, plays indispensable roles in counteracting DNA methylation and facilitating DNA repair, thereby orchestrating methylation …

AlkB homologs (ALKBH) are a family of specific demethylases that depend on Fe 2+ and α-ketoglutarate to catalyze demethylation on different substrates, including ssDNA, dsDNA, …

Abnormal expression of ALKBH members were found in various cancers, and the roles played by it were the focus of attention. The ALKBH gene family encodes nine homologous enzymes …

Apr 19, 2022 · The alpha-ketoglutarate-dependent hydroxylase homolog (ALKBH) proteins, which can remove alkyl and methyl groups from DNAs, have been proposed to function as RNA …

Here we discovered the combined overexpression of members of the ALKBH family in head and neck squamous cell carcinomas (HNSCC). We found direct correlation of ALKBH3 and FTO …