2017年3月2日 · Angioimmunoblastic T-cell lymphoma (AITL) is now a well-established subtype of mature peripheral T-cell lymphoma (PTCL). 1 Many names precede the currently recognized designation by the 2008 World Health Organization classification of lymphoid neoplasms and has been expanded in the 2016 revision. 2 Chronologically acknowledged within the literat...

Angioimmunoblastic T-cell lymphoma (AITL, sometimes misspelled AILT, formerly known as " angioimmunoblastic lymphadenopathy with dysproteinemia " [2]: 747 ) is a mature T-cell lymphoma of blood or lymph vessel immunoblasts characterized by a polymorphous lymph node infiltrate showing a marked increase in follicular dendritic cells (FDCs) and hig...

2024年8月20日 · Angioimmunoblastic T-cell lymphoma (AITL) is a rare, aggressive blood cancer that affects your T cells (a type of white blood cell). Symptoms may include fever, skin rash and painless swelling in your neck, armpit or groin. Common treatments are chemotherapy drugs with steroids and stem cell transplants. Diagnosis usually happens in later stages.

2021年9月5日 · 血管免疫母细胞性T细胞淋巴瘤（AITL）是外周T细胞淋巴瘤的一种亚型，起源于表达CXCL13、CD10 和PD-1的T滤泡辅助细胞，临床较为罕见，仅占外周T细胞淋巴瘤的15% ~20%，以及非霍奇金淋巴瘤的1％～2％ [1]。 我国一项多中心淋巴瘤亚型分布的研究显示AITL在所有淋巴瘤的构成比中仅占2.66％ [2]。 尽管发病率低，AITL却具有进展快、侵袭性高、死亡率及复发率高等特点，预后较差，AITL患者5年总生存率低于40%，5年无进展生存率大约20% [3 …

Angioimmunoblastic T-cell lymphoma (AITL) is a rare and often fast-growing form of peripheral T-cell lymphoma (PTCL). It accounts for about 20-30% of PTCLs and is more common in older people (median age at diagnosis is 65 years), though it can affect young adults as well.

2023年4月24日 · AITL属于全身系统性疾病，临床表现多样，例如淋巴结肿大、肝脾大、皮疹、贫血、多克隆性γ球蛋白血症等；镜下病理组织学形态表现为多种细胞浸润，例如淋巴细胞、浆细胞、嗜酸性粒细胞、组织细胞、中性粒细胞等；特征性表现为高内皮细胞的分枝状静脉增生，滤泡树突细胞增生；细胞起源为滤泡性辅助T细胞（TFH）；分子克隆方面，75%的病例存在TCR基因重排，25%-30%的病例可同时具有免疫球蛋白重链/轻链基因重排，7%的病例仅有重链基因重 …

2021年7月22日 · Angioimmunoblastic T-cell lymphoma (AITL) is a unique subtype of peripheral T-cell lymphoma (PTCL) with distinct clinicopathologic features and poor prognosis. We performed a subset analysis of 282 patients with AITL enrolled between 2006 and 2018 in the international prospective T-cell Project (NCT01142674).

2020年7月23日 · Angioimmunoblastic T-cell lymphoma (AITL) exemplifies a neoplasm characterized by intense inflammatory and immune reactions, as evidenced by its clinical,...

血管免疫母细胞性 t 细胞淋巴瘤 (aitl) 是外周 t 细胞淋巴瘤的亚型——一种非霍奇金淋巴瘤。 aitl 表示癌症起源于淋巴瘤部位血管异常的未成熟免疫细胞（t 细胞）。 aitl 通常具有侵袭性，诊断后需要尽快治疗。

血管免疫母T细胞淋巴瘤（angioimmunoblastic T-cell lymphoma，AITL）是外周T细胞淋巴瘤（peripheral T-cell lymphoma，PTCL）中较为常见的类型，其恶性细胞起源为滤泡辅助T细胞（follicular T helper cell，TFH）。